1-Nitrosoindoline-2-carboxylic acid

Name: 1-Nitrosoindoline-2-carboxylic acid
Brand: Vaqora Chemicals
SKU: VQ-033136

About 1-Nitrosoindoline-2-carboxylic acid

1-Nitrosoindoline-2-carboxylic acid (CAS 192770-68-6) is a nitrosamine impurity of Perindopril offered by Vaqora Chemicals. Formula C9H8N2O3, molecular weight 192.17 g/mol. Its systematic (IUPAC) name is 1-nitroso-2,3-dihydroindole-2-carboxylic acid.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

It is used as a reference standard for trace-level detection and quantitation of nitrosamine impurities by LC-MS/MS or GC-MS, supporting nitrosamine risk assessments for Perindopril, method validation (AMV) and regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 1-Nitrosoindoline-2-carboxylic acid is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Nitrosamine risk assessment
Trace LC-MS/MS quantitation
Method validation (AMV)
Regulatory submissions

Industries

Related to Perindopril

View every impurity, metabolite and intermediate we list for Perindopril.

Perindopril impurities

Specifications & identifiers

Chemical identifiers
Product name	1-Nitrosoindoline-2-carboxylic acid
Catalogue No.	VQ-033136
CAS Number	192770-68-6
IUPAC name	1-nitroso-2,3-dihydroindole-2-carboxylic acid
Molecular formula	C₉H₈N₂O₃
Molecular weight	192.17 g/mol
Exact mass	192.0535
Grade	Reference Standard
HSN code	38229090
InChIKey	IIHPGUYWYDRNLG-UHFFFAOYSA-N
SMILES	C1C(N(C2=CC=CC=C21)N=O)C(=O)O
PubChem CID	45089262

Physical properties
Physical form	Solid
LogP (XLogP3)	1.4
H-bond donors / acceptors	1 / 5
TPSA	70 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 1-Nitrosoindoline-2-carboxylic acid?

The CAS Registry Number of 1-Nitrosoindoline-2-carboxylic acid is 192770-68-6. It is also known as 1-Nitroso-2,3-dihydro-1H-indole-2-carboxylic acid, 2,3-Dihydro-1-nitroso-1H-indole-2-carboxylic acid, 1H-Indole-2-carboxylic acid, 2,3-dihydro-1-nitroso-.

What is the molecular formula and molecular weight of 1-Nitrosoindoline-2-carboxylic acid?

1-Nitrosoindoline-2-carboxylic acid has the molecular formula C9H8N2O3 and a molecular weight of 192.17 g/mol. Its IUPAC name is 1-nitroso-2,3-dihydroindole-2-carboxylic acid.

What is 1-Nitrosoindoline-2-carboxylic acid used for?

1-Nitrosoindoline-2-carboxylic acid is supplied as a characterised reference material related to Perindopril. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 1-Nitrosoindoline-2-carboxylic acid can I order?

We supply 1-Nitrosoindoline-2-carboxylic acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 1-Nitrosoindoline-2-carboxylic acid?

Yes. Every lot of 1-Nitrosoindoline-2-carboxylic acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 1-Nitrosoindoline-2-carboxylic acid be shipped internationally?

Yes. We export 1-Nitrosoindoline-2-carboxylic acid worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.