Lonafarnib

Name: Lonafarnib
Brand: Vaqora Chemicals
SKU: VQ-048920

About Lonafarnib

Lonafarnib (CAS 193275-84-2) is a high-purity reference standard of Lonafarnib offered by Vaqora Chemicals. The compound has the formula C27H31Br2ClN4O2, corresponding to a molecular weight of 638.8 g/mol. Common synonyms include 1o5m and EX-A1630.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

As a reference sample of Lonafarnib, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Lonafarnib

View every impurity, metabolite and intermediate we list for Lonafarnib.

Lonafarnib impurities

Specifications & identifiers

Chemical identifiers
Product name	Lonafarnib
Catalogue No.	VQ-048920
CAS Number	193275-84-2
IUPAC name	4-[2-[4-[(2R)-6,15-dibromo-13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-yl]piperidin-1-yl]-2-oxoethyl]piperidine-1-carboxamide
Molecular formula	C₂₇H₃₁Br₂ClN₄O₂
Molecular weight	638.8 g/mol
Exact mass	638.0482
Grade	Reference Standard
HSN code	38229090
InChIKey	DHMTURDWPRKSOA-RUZDIDTESA-N
SMILES	C1CN(CCC1CC(=O)N2CCC(CC2)[C@@H]3C4=C(CCC5=C3N=CC(=C5)Br)C=C(C=C4Br)Cl)C(=O)N
PubChem CID	148195

Physical properties
Physical form	Solid
LogP (XLogP3)	4.8
H-bond donors / acceptors	1 / 3
TPSA	79.5 Å²

Safety & hazard information (GHS)

Health hazard

Signal word: Warning

Hazard statements

H361Suspected of damaging fertility or the unborn child
H373May causes damage to organs through prolonged or repeated exposure

Precautionary statements: P203, P260, P280, P318, P319, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Lonafarnib?

The CAS Registry Number of Lonafarnib is 193275-84-2. It is also known as 1o5m, EX-A1630.

What is the molecular formula and molecular weight of Lonafarnib?

Lonafarnib has the molecular formula C27H31Br2ClN4O2 and a molecular weight of 638.8 g/mol. Its IUPAC name is 4-[2-[4-[(2R)-6,15-dibromo-13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-yl]piperidin-1-yl]-2-oxoethyl]piperidine-1-carboxamide.

What is Lonafarnib used for?

Lonafarnib is supplied as a characterised reference material related to Lonafarnib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Lonafarnib can I order?

We supply Lonafarnib in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Lonafarnib?

Yes. Every lot of Lonafarnib is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Lonafarnib be shipped internationally?

Yes. Lonafarnib is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.