Tiopronin

About Tiopronin

Tiopronin is a high-purity reference standard of Tiopronin carrying the CAS registry number 1953-02-2. Formula C5H9NO3S, molecular weight 163.2 g/mol. Its systematic (IUPAC) name is 2-(2-sulfanylpropanoylamino)acetic acid. Alternative names: N-(2-Mercaptopropionyl)glycine and Thiopronine.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Laboratories use this Tiopronin standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Tiopronin is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Tiopronin

View every impurity, metabolite and intermediate we list for Tiopronin.

Tiopronin impurities

Specifications & identifiers

Chemical identifiers
Product name	Tiopronin
Catalogue No.	VQ-034285
CAS Number	1953-02-2
IUPAC name	2-(2-sulfanylpropanoylamino)acetic acid
Molecular formula	C₅H₉NO₃S
Molecular weight	163.2 g/mol
Exact mass	163.0303
Grade	Reference Standard
HSN code	38229090
InChIKey	YTGJWQPHMWSCST-UHFFFAOYSA-N
SMILES	CC(C(=O)NCC(=O)O)S
PubChem CID	5483

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.1
H-bond donors / acceptors	3 / 4
TPSA	67.4 Å²
Synonyms	N-(2-Mercaptopropionyl)glycine, Thiopronine, Tiopronine, Glycine, N-(2-mercapto-1-oxopropyl)-, Thiolpropionamidoacetic acid, (2-Mercaptopropionyl)glycine, alpha-Mercaptopropionylglycine, 2-Mercaptopropionylglycine, alpha Mercaptopropionylglycine, 2-Thiolpropionamidoacetic Acid

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Tiopronin?

The CAS Registry Number of Tiopronin is 1953-02-2. It is also known as N-(2-Mercaptopropionyl)glycine, Thiopronine, Tiopronine.

What is the molecular formula and molecular weight of Tiopronin?

Tiopronin has the molecular formula C5H9NO3S and a molecular weight of 163.2 g/mol. Its IUPAC name is 2-(2-sulfanylpropanoylamino)acetic acid.

What is Tiopronin used for?

Tiopronin is supplied as a characterised reference material related to Tiopronin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Tiopronin can I order?

We supply Tiopronin in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Tiopronin?

Yes. Every lot of Tiopronin is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Tiopronin be shipped internationally?

Yes. Tiopronin is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.