1,2,6,7-Tetrahydro-8H-indeno (5,4b) furan-8-o… 196597-78-1

Name: 1,2,6,7-Tetrahydro-8H-indeno (5,4b) furan-8-one
Brand: Vaqora Chemicals
SKU: VQ-027732

About 1,2,6,7-Tetrahydro-8H-indeno (5,4b) furan-8-one

Listed under CAS 196597-78-1, 1,2,6,7-Tetrahydro-8H-indeno (5,4b) furan-8-one is an impurity of Ramelteon available from Vaqora Chemicals. With the molecular formula C11H10O2, it has a molar mass of 174.2 g/mol. Systematically, it is named 1,2,6,7-tetrahydrocyclopenta[e][1]benzofuran-8-one. Alternative names: 6,7-dihydro-1H-indeno[5,4-b]furan-8(2H)-one and 1H,2H,6H,7H,8H-indeno[5,4-b]furan-8-one.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

As a characterised impurity of Ramelteon, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Ramelteon

View every impurity, metabolite and intermediate we list for Ramelteon.

Ramelteon impurities

Specifications & identifiers

Chemical identifiers
Product name	1,2,6,7-Tetrahydro-8H-indeno (5,4b) furan-8-one
Catalogue No.	VQ-027732
CAS Number	196597-78-1
IUPAC name	1,2,6,7-tetrahydrocyclopenta[e][1]benzofuran-8-one
Molecular formula	C₁₁H₁₀O₂
Molecular weight	174.2 g/mol
Exact mass	174.0681
Grade	Reference Standard
HSN code	38229090
InChIKey	ZZUIZMWFNOKNLN-UHFFFAOYSA-N
SMILES	C1CC(=O)C2=C1C=CC3=C2CCO3
PubChem CID	11137616

Physical properties
Physical form	Solid
LogP (XLogP3)	1.7
H-bond donors / acceptors	0 / 2
TPSA	26.3 Å²
Synonyms	8H-Indeno[5,4-b]furan-8-one, 1,2,6,7-tetrahydro-, 8H-Indeno(5,4-b)furan-8-one, 1,2,6,7-tetrahydro-, 6,7-dihydro-1H-indeno[5,4-b]furan-8(2H)-one, 1H,2H,6H,7H,8H-indeno[5,4-b]furan-8-one, 1,2,6,7-tetrahydroindeno[5,4-b]furan-8-one, 1,2,6,7-tetrahydrocyclopenta[e]benzofuran-8-one, CS-B0343, 1,2-dihydroindano[5,4-b]furan-8-one

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 1,2,6,7-Tetrahydro-8H-indeno (5,4b) furan-8-one?

The CAS Registry Number of 1,2,6,7-Tetrahydro-8H-indeno (5,4b) furan-8-one is 196597-78-1. It is also known as 8H-Indeno[5,4-b]furan-8-one, 1,2,6,7-tetrahydro-, 8H-Indeno(5,4-b)furan-8-one, 1,2,6,7-tetrahydro-, 6,7-dihydro-1H-indeno[5,4-b]furan-8(2H)-one.

What is the molecular formula and molecular weight of 1,2,6,7-Tetrahydro-8H-indeno (5,4b) furan-8-one?

1,2,6,7-Tetrahydro-8H-indeno (5,4b) furan-8-one has the molecular formula C11H10O2 and a molecular weight of 174.2 g/mol. Its IUPAC name is 1,2,6,7-tetrahydrocyclopenta[e][1]benzofuran-8-one.

What is 1,2,6,7-Tetrahydro-8H-indeno (5,4b) furan-8-one used for?

1,2,6,7-Tetrahydro-8H-indeno (5,4b) furan-8-one is supplied as a characterised reference material related to Ramelteon. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 1,2,6,7-Tetrahydro-8H-indeno (5,4b) furan-8-one can I order?

We supply 1,2,6,7-Tetrahydro-8H-indeno (5,4b) furan-8-one in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 1,2,6,7-Tetrahydro-8H-indeno (5,4b) furan-8-one?

Yes. Every lot of 1,2,6,7-Tetrahydro-8H-indeno (5,4b) furan-8-one is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 1,2,6,7-Tetrahydro-8H-indeno (5,4b) furan-8-one be shipped internationally?

Yes. 1,2,6,7-Tetrahydro-8H-indeno (5,4b) furan-8-one is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.