(2R,2'R)-6-Fluoro-2-(2'-oxiranyl)chromane

Name: (2R,2'R)-6-Fluoro-2-(2'-oxiranyl)chromane
Brand: Vaqora Chemicals
SKU: VQ-038570

About (2R,2'R)-6-Fluoro-2-(2'-oxiranyl)chromane

Vaqora Chemicals supplies (2R,2'R)-6-Fluoro-2-(2'-oxiranyl)chromane, an impurity of Nebivolol registered under CAS number 197706-50-6. With the molecular formula C11H11FO2, it has a molar mass of 194.2 g/mol. The IUPAC name is (2R)-6-fluoro-2-[(2R)-oxiran-2-yl]-3,4-dihydro-2H-chromene. Alternative names: (R)-6-fluoro-2-((R)-oxiran-2-yl)chroman and (R)-6-Fluoro-2-((R)-oxiran-2-yl)chromane.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Nebivolol to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, (2R,2'R)-6-Fluoro-2-(2'-oxiranyl)chromane is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Nebivolol

View every impurity, metabolite and intermediate we list for Nebivolol.

Nebivolol impurities

Specifications & identifiers

Chemical identifiers
Product name	(2R,2'R)-6-Fluoro-2-(2'-oxiranyl)chromane
Catalogue No.	VQ-038570
CAS Number	197706-50-6
IUPAC name	(2R)-6-fluoro-2-[(2R)-oxiran-2-yl]-3,4-dihydro-2H-chromene
Molecular formula	C₁₁H₁₁FO₂
Molecular weight	194.2 g/mol
Exact mass	194.0743
Grade	Reference Standard
HSN code	38229090
InChIKey	GVZDIJGBXSDSEP-GHMZBOCLSA-N
SMILES	C1CC2=C(C=CC(=C2)F)O[C@H]1[C@H]3CO3
PubChem CID	11356016

Physical properties
Physical form	Solid
LogP (XLogP3)	2.1
H-bond donors / acceptors	0 / 3
TPSA	21.8 Å²
Synonyms	(2R)-6-Fluoro-3,4-dihydro-2-((2R)-2-oxiranyl)-2H-1-benzopyran, (2R)-6-Fluoro-3,4-dihydro-2-[(2R)-2-oxiranyl]-2H-1-benzopyran, (R)-6-fluoro-3,4-dihydro-2-((R)-oxiran-2-yl)-2H-chromene, (2R)-6-fluoro-2-[(2S)-oxiran-2-yl]-3,4-dihydro-2H-chromene, (R)-6-fluoro-2-((R)-oxiran-2-yl)chroman, 2H-1-Benzopyran, 6-fluoro-3,4-dihydro-2-(2R)-2-oxiranyl-, (2R)-rel-, (R)-6-Fluoro-2-((R)-oxiran-2-yl)chromane, (2R)-6-Fluoro-2-[(2R)-2-oxiranyl]chromane, (2R)-6-Fluoro-2-[(2S)-2-oxiranyl]chromane, rel-(R)-6-Fluoro-2-((R)-oxiran-2-yl)chromane, (R)-6-fluoro-3,4-dihydro((R)-oxiran-2-yl)-2H-chromen

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (2R,2'R)-6-Fluoro-2-(2'-oxiranyl)chromane?

The CAS Registry Number of (2R,2'R)-6-Fluoro-2-(2'-oxiranyl)chromane is 197706-50-6. It is also known as (2R)-6-Fluoro-3,4-dihydro-2-((2R)-2-oxiranyl)-2H-1-benzopyran, (2R)-6-Fluoro-3,4-dihydro-2-[(2R)-2-oxiranyl]-2H-1-benzopyran, (R)-6-fluoro-3,4-dihydro-2-((R)-oxiran-2-yl)-2H-chromene.

What is the molecular formula and molecular weight of (2R,2'R)-6-Fluoro-2-(2'-oxiranyl)chromane?

(2R,2'R)-6-Fluoro-2-(2'-oxiranyl)chromane has the molecular formula C11H11FO2 and a molecular weight of 194.2 g/mol. Its IUPAC name is (2R)-6-fluoro-2-[(2R)-oxiran-2-yl]-3,4-dihydro-2H-chromene.

What is (2R,2'R)-6-Fluoro-2-(2'-oxiranyl)chromane used for?

(2R,2'R)-6-Fluoro-2-(2'-oxiranyl)chromane is supplied as a characterised reference material related to Nebivolol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (2R,2'R)-6-Fluoro-2-(2'-oxiranyl)chromane can I order?

We supply (2R,2'R)-6-Fluoro-2-(2'-oxiranyl)chromane in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (2R,2'R)-6-Fluoro-2-(2'-oxiranyl)chromane?

Yes. Every lot of (2R,2'R)-6-Fluoro-2-(2'-oxiranyl)chromane is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (2R,2'R)-6-Fluoro-2-(2'-oxiranyl)chromane be shipped internationally?

Yes. We export (2R,2'R)-6-Fluoro-2-(2'-oxiranyl)chromane worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.