5-β-Hydroxy Drospirenone

Name: 5-β-Hydroxy Drospirenone
Brand: Vaqora Chemicals
SKU: VQ-022462

About 5-β-Hydroxy Drospirenone

5-β-Hydroxy Drospirenone (CAS 197721-70-3) is a metabolite or degradation product of Drospirenone offered by Vaqora Chemicals. Formula C24H32O4, molecular weight 384.5 g/mol. It is also known as 5beta-Hydroxy Drospirenone or 5-beta-Hydroxy Drospirenone Lactone.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Analytical teams use this compound to identify metabolites and degradants of Drospirenone, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer 5-β-Hydroxy Drospirenone in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Drospirenone

View every impurity, metabolite and intermediate we list for Drospirenone.

Drospirenone impurities

Specifications & identifiers

Chemical identifiers
Product name	5-β-Hydroxy Drospirenone
Catalogue No.	VQ-022462
CAS Number	197721-70-3
IUPAC name	(1R,2R,4R,5R,10R,11S,14S,15S,16S,18S,19S)-5-hydroxy-10,14-dimethylspiro[hexacyclo[9.8.0.02,4.05,10.014,19.016,18]nonadecane-15,5'-oxolane]-2',7-dione
Molecular formula	C₂₄H₃₂O₄
Molecular weight	384.5 g/mol
Exact mass	384.2301
Grade	Reference Standard
HSN code	38229090
InChIKey	RQANBDIXNMIXPA-DHHRPGCOSA-N
SMILES	C[C@]12CCC(=O)C[C@]1([C@@H]3C[C@@H]3[C@@H]4[C@@H]2CC[C@]5([C@H]4[C@@H]6C[C@@H]6[C@@]57CCC(=O)O7)C)O
PubChem CID	15516076

Physical properties
Physical form	Solid
LogP (XLogP3)	2.7
H-bond donors / acceptors	1 / 4
TPSA	63.6 Å²

Safety & hazard information (GHS)

Environmental hazard

Hazard statements

H411Toxic to aquatic life with long lasting effects

Precautionary statements: P273, P391, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 5-β-Hydroxy Drospirenone?

The CAS Registry Number of 5-β-Hydroxy Drospirenone is 197721-70-3. It is also known as 5beta-Hydroxy Drospirenone, 5-beta-Hydroxy Drospirenone Lactone, 5b-Hydroxy Drospirenone.

What is the molecular formula and molecular weight of 5-β-Hydroxy Drospirenone?

5-β-Hydroxy Drospirenone has the molecular formula C24H32O4 and a molecular weight of 384.5 g/mol. Its IUPAC name is (1R,2R,4R,5R,10R,11S,14S,15S,16S,18S,19S)-5-hydroxy-10,14-dimethylspiro[hexacyclo[9.8.0.02,4.05,10.014,19.016,18]nonadecane-15,5'-oxolane]-2',7-dione.

What is 5-β-Hydroxy Drospirenone used for?

5-β-Hydroxy Drospirenone is supplied as a characterised reference material related to Drospirenone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 5-β-Hydroxy Drospirenone can I order?

We supply 5-β-Hydroxy Drospirenone in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 5-β-Hydroxy Drospirenone?

Yes. Every lot of 5-β-Hydroxy Drospirenone is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 5-β-Hydroxy Drospirenone be shipped internationally?

Yes. 5-β-Hydroxy Drospirenone is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.