4-(difluoromethyl)aniline hydrochloride

Name: 4-(difluoromethyl)aniline hydrochloride
Brand: Vaqora Chemicals
SKU: VQ-013070

About 4-(difluoromethyl)aniline hydrochloride

Listed under CAS 1980063-54-4, 4-(difluoromethyl)aniline hydrochloride is a process intermediate or related compound of Teriflunomide available from Vaqora Chemicals. With the molecular formula C7H8ClF2N, it has a molar mass of 179.59 g/mol. Alternative names: 4-(Difluoromethyl)benzenamine hydrochloride and 4-(Difluoromethyl)anilinehydrochloride.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 6 hazard statements. Review the Safety Data Sheet before use.

It is a process intermediate or related compound in the synthesis of Teriflunomide, useful for route development, impurity fate-and-purge studies and analytical method development. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. This item is currently in stock for prompt dispatch.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Teriflunomide

View every impurity, metabolite and intermediate we list for Teriflunomide.

Teriflunomide impurities

Specifications & identifiers

Chemical identifiers
Product name	4-(difluoromethyl)aniline hydrochloride
Catalogue No.	VQ-013070
CAS Number	1980063-54-4
Other CAS	49658-26-6
IUPAC name	4-(difluoromethyl)aniline;hydrochloride
Molecular formula	C₇H₈ClF₂N
Molecular weight	179.59 g/mol
Exact mass	179.0313
Grade	Reference Standard
HSN code	2933
InChIKey	ONCQIBIEQYPTRG-UHFFFAOYSA-N
SMILES	C1=CC(=CC=C1C(F)F)N.Cl
PubChem CID	67958831

Physical properties
Physical form	Solid
H-bond donors / acceptors	2 / 3
TPSA	26 Å²

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-(difluoromethyl)aniline hydrochloride?

The CAS Registry Number of 4-(difluoromethyl)aniline hydrochloride is 1980063-54-4. It is also known as 4-(Difluoromethyl)benzenamine hydrochloride, alpha,alpha-Difluoro-p-toluidine hydrochloride, 4-(Difluoromethyl)anilinehydrochloride.

What is the molecular formula and molecular weight of 4-(difluoromethyl)aniline hydrochloride?

4-(difluoromethyl)aniline hydrochloride has the molecular formula C7H8ClF2N and a molecular weight of 179.59 g/mol.

What is 4-(difluoromethyl)aniline hydrochloride used for?

4-(difluoromethyl)aniline hydrochloride is supplied as a characterised reference material related to Teriflunomide. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-(difluoromethyl)aniline hydrochloride can I order?

We supply 4-(difluoromethyl)aniline hydrochloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-(difluoromethyl)aniline hydrochloride?

Yes. Every lot of 4-(difluoromethyl)aniline hydrochloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-(difluoromethyl)aniline hydrochloride be shipped internationally?

Yes. 4-(difluoromethyl)aniline hydrochloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.