N-Acetyl-L-phenylalanine

About N-Acetyl-L-phenylalanine

N-Acetyl-L-phenylalanine is an impurity of Aspartame carrying the CAS registry number 2018-61-3. The compound has the formula C11H13NO3, corresponding to a molecular weight of 207.23 g/mol. Systematically, it is named (2S)-2-acetamido-3-phenylpropanoic acid. Common synonyms include Acetyl-L-phenylalanine and L-Phenylalanine, N-acetyl-.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Warning” with 3 hazard statements. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Aspartame to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, N-Acetyl-L-phenylalanine is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Aspartame

View every impurity, metabolite and intermediate we list for Aspartame.

Aspartame impurities

Specifications & identifiers

Chemical identifiers
Product name	N-Acetyl-L-phenylalanine
Catalogue No.	VQ-024378
CAS Number	2018-61-3
IUPAC name	(2S)-2-acetamido-3-phenylpropanoic acid
Molecular formula	C₁₁H₁₃NO₃
Molecular weight	207.23 g/mol
Exact mass	207.0895
Grade	Reference Standard
HSN code	38229090
InChIKey	CBQJSKKFNMDLON-JTQLQIEISA-N
SMILES	CC(=O)N[C@@H](CC1=CC=CC=C1)C(=O)O
PubChem CID	74839

Physical properties
Physical form	Solid
LogP (XLogP3)	0.6
H-bond donors / acceptors	2 / 3
TPSA	66.4 Å²
Synonyms	Acetyl-L-phenylalanine, L-Phenylalanine, N-acetyl-, N-Acetylphenylalanine, L-N-Acetylphenylalanine, acetylphenylalanine, Alanine, N-acetyl-3-phenyl-, L-, (2S)-2-acetamido-3-phenylpropanoate, Ac-Phe-OH, (S)-2-Acetamido-3-phenylpropanoic acid, Phenylalanine, N-acetyl-, N-Acetyl-3-phenyl-L-alanine, N-Acetyl-l-phenalanine

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Acetyl-L-phenylalanine?

The CAS Registry Number of N-Acetyl-L-phenylalanine is 2018-61-3. It is also known as Acetyl-L-phenylalanine, L-Phenylalanine, N-acetyl-, N-Acetylphenylalanine.

What is the molecular formula and molecular weight of N-Acetyl-L-phenylalanine?

N-Acetyl-L-phenylalanine has the molecular formula C11H13NO3 and a molecular weight of 207.23 g/mol. Its IUPAC name is (2S)-2-acetamido-3-phenylpropanoic acid.

What is N-Acetyl-L-phenylalanine used for?

N-Acetyl-L-phenylalanine is supplied as a characterised reference material related to Aspartame. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-Acetyl-L-phenylalanine can I order?

We supply N-Acetyl-L-phenylalanine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Acetyl-L-phenylalanine?

Yes. Every lot of N-Acetyl-L-phenylalanine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Acetyl-L-phenylalanine be shipped internationally?

Yes. N-Acetyl-L-phenylalanine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.