27-Hydroxycholesterol

Name: 27-Hydroxycholesterol
Brand: Vaqora Chemicals
SKU: VQ-047773

About 27-Hydroxycholesterol

27-Hydroxycholesterol (CAS 20380-11-4) is a metabolite or degradation product of Cholesterol offered by Vaqora Chemicals. The compound has the formula C27H46O2, corresponding to a molecular weight of 402.7 g/mol. It is also known as (25R)-26-Hydroxycholesterol or (25R)-Cholest-5-ene-3beta,26-diol.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Analytical teams use this compound to identify metabolites and degradants of Cholesterol, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer 27-Hydroxycholesterol in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Cholesterol

View every impurity, metabolite and intermediate we list for Cholesterol.

Cholesterol impurities

Specifications & identifiers

Chemical identifiers
Product name	27-Hydroxycholesterol
Catalogue No.	VQ-047773
CAS Number	20380-11-4
IUPAC name	(3S,8S,9S,10R,13R,14S,17R)-17-[(2R,6R)-7-hydroxy-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
Molecular formula	C₂₇H₄₆O₂
Molecular weight	402.7 g/mol
Exact mass	402.3498
Grade	Reference Standard
HSN code	38229090
InChIKey	FYHRJWMENCALJY-YSQMORBQSA-N
SMILES	C[C@H](CCC[C@@H](C)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC=C4[C@@]3(CC[C@@H](C4)O)C)C)CO
PubChem CID	123976

Physical properties
Physical form	Solid
LogP (XLogP3)	7.1
H-bond donors / acceptors	2 / 2
TPSA	40.5 Å²
Synonyms	(25R)-26-Hydroxycholesterol, (25R)-Cholest-5-ene-3beta,26-diol, Cholest-5-ene-3beta,27-diol, 5-cholestene-3 beta,27-diol, 27HC, (3beta,25R)-cholest-5-ene-3,26-diol, Cholest-5-ene-3beta,26-diol, (25R)-, Cholest-5-ene-3,26,diol, (3beta,25R)-, 26-hydroxycholesterol, (25R), cholest-5-ene-3 beta,27-diol, (25R)-cholest-5-ene-3 beta,26-diol, (3 beta,25R)-cholest-5-ene-3,26-diol

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 27-Hydroxycholesterol?

The CAS Registry Number of 27-Hydroxycholesterol is 20380-11-4. It is also known as (25R)-26-Hydroxycholesterol, (25R)-Cholest-5-ene-3beta,26-diol, Cholest-5-ene-3beta,27-diol.

What is the molecular formula and molecular weight of 27-Hydroxycholesterol?

27-Hydroxycholesterol has the molecular formula C27H46O2 and a molecular weight of 402.7 g/mol. Its IUPAC name is (3S,8S,9S,10R,13R,14S,17R)-17-[(2R,6R)-7-hydroxy-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol.

What is 27-Hydroxycholesterol used for?

27-Hydroxycholesterol is supplied as a characterised reference material related to Cholesterol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 27-Hydroxycholesterol can I order?

We supply 27-Hydroxycholesterol in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 27-Hydroxycholesterol?

Yes. Every lot of 27-Hydroxycholesterol is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 27-Hydroxycholesterol be shipped internationally?

Yes. We export 27-Hydroxycholesterol worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.