2-Methyl-2-(p-tolyl)propanoic Acid

Name: 2-Methyl-2-(p-tolyl)propanoic Acid
Brand: Vaqora Chemicals
SKU: VQ-047584

About 2-Methyl-2-(p-tolyl)propanoic Acid

2-Methyl-2-(p-tolyl)propanoic Acid (CAS 20430-18-6) is a process intermediate or related compound of Bilastine offered by Vaqora Chemicals. With the molecular formula C11H14O2, it has a molar mass of 178.23 g/mol. Its systematic (IUPAC) name is 2-methyl-2-(4-methylphenyl)propanoic acid. Common synonyms include Benzeneacetic acid, alpha,alpha,4-trimethyl- and 2-Methyl-2-p-tolyl-propionic acid.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Warning” with 4 hazard statements. Review the Safety Data Sheet before use.

Process chemists and analysts use it when developing synthetic routes to Bilastine, tracking process-related impurities and validating analytical methods. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer 2-Methyl-2-(p-tolyl)propanoic Acid in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Bilastine

View every impurity, metabolite and intermediate we list for Bilastine.

Bilastine impurities

Specifications & identifiers

Chemical identifiers
Product name	2-Methyl-2-(p-tolyl)propanoic Acid
Catalogue No.	VQ-047584
CAS Number	20430-18-6
IUPAC name	2-methyl-2-(4-methylphenyl)propanoic acid
Molecular formula	C₁₁H₁₄O₂
Molecular weight	178.23 g/mol
Exact mass	178.0994
InChIKey	SHDBWXXRCCHGQD-UHFFFAOYSA-N
SMILES	CC1=CC=C(C=C1)C(C)(C)C(=O)O
PubChem CID	12369085

Physical properties
Physical form	Solid
LogP (XLogP3)	2.7
H-bond donors / acceptors	1 / 2
TPSA	37.3 Å²
Synonyms	Benzeneacetic acid, alpha,alpha,4-trimethyl-, 2-Methyl-2-p-tolyl-propionic acid, Dimethyl-p-tolylessigsaure, Benzeneacetic acid,, A,, A,4-trimethyl-, 2-(4-methylphenyl)-2-methylpropionic acid

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H303May be harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2-Methyl-2-(p-tolyl)propanoic Acid?

The CAS Registry Number of 2-Methyl-2-(p-tolyl)propanoic Acid is 20430-18-6. It is also known as Benzeneacetic acid, alpha,alpha,4-trimethyl-, 2-Methyl-2-p-tolyl-propionic acid, Dimethyl-p-tolylessigsaure.

What is the molecular formula and molecular weight of 2-Methyl-2-(p-tolyl)propanoic Acid?

2-Methyl-2-(p-tolyl)propanoic Acid has the molecular formula C11H14O2 and a molecular weight of 178.23 g/mol. Its IUPAC name is 2-methyl-2-(4-methylphenyl)propanoic acid.

What is 2-Methyl-2-(p-tolyl)propanoic Acid used for?

2-Methyl-2-(p-tolyl)propanoic Acid is supplied as a characterised reference material related to Bilastine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2-Methyl-2-(p-tolyl)propanoic Acid can I order?

We supply 2-Methyl-2-(p-tolyl)propanoic Acid, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2-Methyl-2-(p-tolyl)propanoic Acid?

Yes. Every lot of 2-Methyl-2-(p-tolyl)propanoic Acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2-Methyl-2-(p-tolyl)propanoic Acid be shipped internationally?

Yes. 2-Methyl-2-(p-tolyl)propanoic Acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.