2-((6-Chloro-2-methylpyrimidin-4-yl)amino)-N-… 2048106-50-7

About 2-((6-Chloro-2-methylpyrimidin-4-yl)amino)-N-(2-(4-(2-hydroxyethyl)piperazin-1-yl)-6-methylphenyl)thiazole-5-carboxamide

2-((6-Chloro-2-methylpyrimidin-4-yl)amino)-N-(2-(4-(2-hydroxyethyl)piperazin-1-yl)-6-methylphenyl)thiazole-5-carboxamide is a metabolite or degradation product of Dasatinib carrying the CAS registry number 2048106-50-7. Its molecular formula is C22H26ClN7O2S and its molecular weight is 488.0 g/mol.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Dasatinib, as well as in QC testing and ANDA/DMF documentation. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 2-((6-Chloro-2-methylpyrimidin-4-yl)amino)-N-(2-(4-(2-hydroxyethyl)piperazin-1-yl)-6-methylphenyl)thiazole-5-carboxamide is dispatched with a Certificate of Analysis (COA) to destinations worldwide. SDS and detailed specification sheets can be requested with your quotation.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Dasatinib

View every impurity, metabolite and intermediate we list for Dasatinib.

Dasatinib impurities

Specifications & identifiers

Chemical identifiers
Product name	2-((6-Chloro-2-methylpyrimidin-4-yl)amino)-N-(2-(4-(2-hydroxyethyl)piperazin-1-yl)-6-methylphenyl)thiazole-5-carboxamide
Catalogue No.	VQ-047969
CAS Number	2048106-50-7
IUPAC name	2-[(6-chloro-2-methylpyrimidin-4-yl)amino]-N-[2-[4-(2-hydroxyethyl)piperazin-1-yl]-6-methylphenyl]-1,3-thiazole-5-carboxamide
Molecular formula	C₂₂H₂₆ClN₇O₂S
Molecular weight	488 g/mol
Exact mass	487.1557
Grade	Reference Standard
HSN code	38229090
InChIKey	SHLKHEYDLZWBLF-UHFFFAOYSA-N
SMILES	CC1=C(C(=CC=C1)N2CCN(CC2)CCO)NC(=O)C3=CN=C(S3)NC4=CC(=NC(=N4)C)Cl
PubChem CID	154631479

Physical properties
Physical form	Solid
LogP (XLogP3)	3.6
H-bond donors / acceptors	3 / 9
TPSA	135 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2-((6-Chloro-2-methylpyrimidin-4-yl)amino)-N-(2-(4-(2-hydroxyethyl)piperazin-1-yl)-6-methylphenyl)thiazole-5-carboxamide?

The CAS Registry Number of 2-((6-Chloro-2-methylpyrimidin-4-yl)amino)-N-(2-(4-(2-hydroxyethyl)piperazin-1-yl)-6-methylphenyl)thiazole-5-carboxamide is 2048106-50-7.

What is the molecular formula and molecular weight of 2-((6-Chloro-2-methylpyrimidin-4-yl)amino)-N-(2-(4-(2-hydroxyethyl)piperazin-1-yl)-6-methylphenyl)thiazole-5-carboxamide?

2-((6-Chloro-2-methylpyrimidin-4-yl)amino)-N-(2-(4-(2-hydroxyethyl)piperazin-1-yl)-6-methylphenyl)thiazole-5-carboxamide has the molecular formula C22H26ClN7O2S and a molecular weight of 488 g/mol. Its IUPAC name is 2-[(6-chloro-2-methylpyrimidin-4-yl)amino]-N-[2-[4-(2-hydroxyethyl)piperazin-1-yl]-6-methylphenyl]-1,3-thiazole-5-carboxamide.

What is 2-((6-Chloro-2-methylpyrimidin-4-yl)amino)-N-(2-(4-(2-hydroxyethyl)piperazin-1-yl)-6-methylphenyl)thiazole-5-carboxamide used for?

2-((6-Chloro-2-methylpyrimidin-4-yl)amino)-N-(2-(4-(2-hydroxyethyl)piperazin-1-yl)-6-methylphenyl)thiazole-5-carboxamide is supplied as a characterised reference material related to Dasatinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2-((6-Chloro-2-methylpyrimidin-4-yl)amino)-N-(2-(4-(2-hydroxyethyl)piperazin-1-yl)-6-methylphenyl)thiazole-5-carboxamide can I order?

We supply 2-((6-Chloro-2-methylpyrimidin-4-yl)amino)-N-(2-(4-(2-hydroxyethyl)piperazin-1-yl)-6-methylphenyl)thiazole-5-carboxamide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2-((6-Chloro-2-methylpyrimidin-4-yl)amino)-N-(2-(4-(2-hydroxyethyl)piperazin-1-yl)-6-methylphenyl)thiazole-5-carboxamide?

Yes. Every lot of 2-((6-Chloro-2-methylpyrimidin-4-yl)amino)-N-(2-(4-(2-hydroxyethyl)piperazin-1-yl)-6-methylphenyl)thiazole-5-carboxamide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2-((6-Chloro-2-methylpyrimidin-4-yl)amino)-N-(2-(4-(2-hydroxyethyl)piperazin-1-yl)-6-methylphenyl)thiazole-5-carboxamide be shipped internationally?

Yes. We export 2-((6-Chloro-2-methylpyrimidin-4-yl)amino)-N-(2-(4-(2-hydroxyethyl)piperazin-1-yl)-6-methylphenyl)thiazole-5-carboxamide worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.