DMT-locA(bz) Phosphoramidite

About DMT-locA(bz) Phosphoramidite

DMT-locA(bz) Phosphoramidite is an imidazole derivative carrying the CAS registry number 206055-79-0. Its molecular formula is C48H52N7O8P and its molecular weight is 885.9 g/mol. Common synonyms include LNA-A(Bz) amidite and DMTr-LNA-A(Bz)-3-CED-phosphoramidite.

Store sealed in a dry, well-ventilated location away from incompatible materials. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Key uses span organic synthesis and API synthesis. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 100 mg, 250 mg, 1 g and 5 g, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. A Safety Data Sheet (SDS) and technical specifications are available on request. Custom pack sizes, bulk quantities and specific analytical data can be arranged on request.

Typical applications

Organic synthesis
API synthesis

Industries

Specifications & identifiers

Chemical identifiers
Product name	DMT-locA(bz) Phosphoramidite
Catalogue No.	VQ-051946
CAS Number	206055-79-0
IUPAC name	N-[9-[(1R,3R,4R,7S)-1-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-7-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-2,5-dioxabicyclo[2.2.1]heptan-3-yl]purin-6-yl]benzamide
Molecular formula	C₄₈H₅₂N₇O₈P
Molecular weight	885.9 g/mol
Exact mass	885.3615
HSN code	2933
InChIKey	HPIDKMAOZZZGOP-LIUGLABVSA-N
SMILES	CC(C)N(C(C)C)P(OCCC#N)O[C@H]1[C@@H]2[C@@H](O[C@]1(CO2)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)N6C=NC7=C(N=CN=C76)NC(=O)C8=CC=CC=C8
PubChem CID	13009021

Physical properties
Physical form	Other
LogP (XLogP3)	6.3
H-bond donors / acceptors	1 / 13
TPSA	164 Å²
Synonyms	LNA-A(Bz) amidite, DMTr-LNA-A(Bz)-3-CED-phosphoramidite, EX-A7174A, DMT-locA(bz)Amidite 1g, 89, Single, DMT-locA(bz)Amidite 0.25g, 89, Single, 2'-O-4'-C-Locked-Bz-A-CE Phosphoramidite, 2'-O-4'-C-Locked-A(Bz)-CE Phosphoramidite, DMT-2'-O-4'-C-Locked-A(Bz)-CE-Phosphoramidite, N6-Bz-2'-O-4'-A-Locked-Ar-CE-Phosphoramidite, N6-Bz-2'-O-4'-C-Locked-Ar-CE-Phosphoramidite, N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-LNA-adenosine-3'-cyanoethyl phosphoramidite

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H319Causes serious eye irritation

Precautionary statements: P264 + P265, P280, P305 + P351 + P338, P337 + P317

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of DMT-locA(bz) Phosphoramidite?

The CAS Registry Number of DMT-locA(bz) Phosphoramidite is 206055-79-0. It is also known as LNA-A(Bz) amidite, DMTr-LNA-A(Bz)-3-CED-phosphoramidite, EX-A7174A.

What is the molecular formula and molecular weight of DMT-locA(bz) Phosphoramidite?

DMT-locA(bz) Phosphoramidite has the molecular formula C48H52N7O8P and a molecular weight of 885.9 g/mol.

Which grade and pack sizes of DMT-locA(bz) Phosphoramidite can I order?

We supply DMT-locA(bz) Phosphoramidite, in 100 mg, 250 mg, 1 g, 5 g packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with DMT-locA(bz) Phosphoramidite?

Yes. Every lot of DMT-locA(bz) Phosphoramidite is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can DMT-locA(bz) Phosphoramidite be shipped internationally?

Yes. DMT-locA(bz) Phosphoramidite is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.