D-Penicillamine Disulfide

About D-Penicillamine Disulfide

D-Penicillamine Disulfide is an impurity of Penicillamine carrying the CAS registry number 20902-45-8. The compound has the formula C10H20N2O4S2, corresponding to a molecular weight of 296.4 g/mol. Its systematic (IUPAC) name is (2S)-2-amino-3-[[(1S)-1-amino-1-carboxy-2-methylpropan-2-yl]disulfanyl]-3-methylbutanoic acid. Common synonyms include Penicillamine Disulfide and 3,3'-Dithiodi-D-valine.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

This Penicillamine impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer D-Penicillamine Disulfide in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Penicillamine

View every impurity, metabolite and intermediate we list for Penicillamine.

Penicillamine impurities

Specifications & identifiers

Chemical identifiers
Product name	D-Penicillamine Disulfide
Catalogue No.	VQ-033096
CAS Number	20902-45-8
IUPAC name	(2S)-2-amino-3-[[(1S)-1-amino-1-carboxy-2-methylpropan-2-yl]disulfanyl]-3-methylbutanoic acid
Molecular formula	C₁₀H₂₀N₂O₄S₂
Molecular weight	296.4 g/mol
Exact mass	296.0864
Grade	Reference Standard
HSN code	38229090
InChIKey	POYPKGFSZHXASD-WDSKDSINSA-N
SMILES	CC(C)([C@H](C(=O)O)N)SSC(C)(C)[C@H](C(=O)O)N
PubChem CID	9882671

Physical properties
Physical form	Solid
LogP (XLogP3)	-5
H-bond donors / acceptors	4 / 8
TPSA	177 Å²
Synonyms	Penicillamine Disulfide, (2S,2'S)-3,3'-disulfanediylbis(2-amino-3-methylbutanoic acid), 3,3'-Dithiodi-D-valine, S,S'-Bi(D-penicillamine), 3,3,3,',3'-tetramethyl-D-cystine, (2S,2'S)-3,3'-dithiobis(2-amino-3-methylbutyric acid), (2S,2'S)-3,3'-dithiobis(2-amino-3-methylbutanoic acid), 3,3'-Dithiobis(2-amino-3-methylbutyric acid), D-Valine, 3,3'-dithiobis-, Penicillamine disulfide D-form

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of D-Penicillamine Disulfide?

The CAS Registry Number of D-Penicillamine Disulfide is 20902-45-8. It is also known as Penicillamine Disulfide, (2S,2'S)-3,3'-disulfanediylbis(2-amino-3-methylbutanoic acid), 3,3'-Dithiodi-D-valine.

What is the molecular formula and molecular weight of D-Penicillamine Disulfide?

D-Penicillamine Disulfide has the molecular formula C10H20N2O4S2 and a molecular weight of 296.4 g/mol. Its IUPAC name is (2S)-2-amino-3-[[(1S)-1-amino-1-carboxy-2-methylpropan-2-yl]disulfanyl]-3-methylbutanoic acid.

What is D-Penicillamine Disulfide used for?

D-Penicillamine Disulfide is supplied as a characterised reference material related to Penicillamine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of D-Penicillamine Disulfide can I order?

We supply D-Penicillamine Disulfide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with D-Penicillamine Disulfide?

Yes. Every lot of D-Penicillamine Disulfide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can D-Penicillamine Disulfide be shipped internationally?

Yes. D-Penicillamine Disulfide is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.