Ziftomenib

Name: Ziftomenib
Brand: Vaqora Chemicals
SKU: VQ-034737

About Ziftomenib

Vaqora Chemicals supplies Ziftomenib, an API impurity reference standard registered under CAS number 2134675-36-6. Its molecular formula is C33H42F3N9O2S2 and its molecular weight is 717.9 g/mol. Alternative names: KO-539 and Ko 539.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of the parent drug substance to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer Ziftomenib in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Specifications & identifiers

Chemical identifiers
Product name	Ziftomenib
Catalogue No.	VQ-034737
CAS Number	2134675-36-6
IUPAC name	4-methyl-5-[[4-[[2-(methylamino)-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]-1-[(2S)-2-(4-methylsulfonylpiperazin-1-yl)propyl]indole-2-carbonitrile
Molecular formula	C₃₃H₄₂F₃N₉O₂S₂
Molecular weight	717.9 g/mol
Exact mass	717.2855
Grade	Reference Standard
HSN code	38229090
InChIKey	BGGALFIXXQOTPY-NRFANRHFSA-N
SMILES	CC1=C(C=CC2=C1C=C(N2C[C@H](C)N3CCN(CC3)S(=O)(=O)C)C#N)CN4CCC(CC4)NC5=C6C=C(SC6=NC(=N5)NC)CC(F)(F)F
PubChem CID	138497449

Physical properties
Physical form	Solid
LogP (XLogP3)	5.6
H-bond donors / acceptors	2 / 14
TPSA	159 Å²
Synonyms	KO-539, Ko 539, compound 151 [US10781218B2], Menin-Mixed Lineage Leukemia Protein-Protein Interaction Inhibitor KO 539, compound 151 (US10781218B2), Menin-MLL Inhibitor KO-539, Menin-KMT2A Inhibitor KO 539, Menin-mll interaction inhibitor KO 539, EX-A5611

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Ziftomenib?

The CAS Registry Number of Ziftomenib is 2134675-36-6. It is also known as KO-539, Ko 539, compound 151 [US10781218B2].

What is the molecular formula and molecular weight of Ziftomenib?

Ziftomenib has the molecular formula C33H42F3N9O2S2 and a molecular weight of 717.9 g/mol.

Which grade and pack sizes of Ziftomenib can I order?

We supply Ziftomenib in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ziftomenib?

Yes. Every lot of Ziftomenib is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ziftomenib be shipped internationally?

Yes. We export Ziftomenib worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.