25-Hydroxy Cholesterol

Name: 25-Hydroxy Cholesterol
Brand: Vaqora Chemicals
SKU: VQ-024954

About 25-Hydroxy Cholesterol

Vaqora Chemicals supplies 25-Hydroxy Cholesterol, a metabolite or degradation product of Cholesterol registered under CAS number 2140-46-7. Its molecular formula is C27H46O2 and its molecular weight is 402.7 g/mol. It is also known as Cholest-5-ene-3beta,25-diol or 5-Cholestene-3beta,25-diol.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Warning” with 7 hazard statements. Review the Safety Data Sheet before use.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Cholesterol, as well as in QC testing and ANDA/DMF documentation. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Cholesterol

View every impurity, metabolite and intermediate we list for Cholesterol.

Cholesterol impurities

Specifications & identifiers

Chemical identifiers
Product name	25-Hydroxy Cholesterol
Catalogue No.	VQ-024954
CAS Number	2140-46-7
IUPAC name	(3S,8S,9S,10R,13R,14S,17R)-17-[(2R)-6-hydroxy-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
Molecular formula	C₂₇H₄₆O₂
Molecular weight	402.7 g/mol
Exact mass	402.3498
Grade	Reference Standard
HSN code	38229090
InChIKey	INBGSXNNRGWLJU-ZHHJOTBYSA-N
SMILES	C[C@H](CCCC(C)(C)O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC=C4[C@@]3(CC[C@@H](C4)O)C)C
PubChem CID	65094

Physical properties
Physical form	Solid
LogP (XLogP3)	6.8
H-bond donors / acceptors	2 / 2
TPSA	40.5 Å²
Synonyms	Cholest-5-ene-3beta,25-diol, 5-Cholestene-3beta,25-diol, 25-OHC, 5-cholesten-3beta,25-diol, cholest-5-ene-3 beta,25-diol, cholest-5-en-3beta,25-diol, Cholest-5-ene-3,25-diol, 25-Hydroxycholest-5-en-3-ol, Cholest-5-ene-3,25-diol, (3b)-

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
H373May causes damage to organs through prolonged or repeated exposure

Precautionary statements: P260, P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 25-Hydroxy Cholesterol?

The CAS Registry Number of 25-Hydroxy Cholesterol is 2140-46-7. It is also known as Cholest-5-ene-3beta,25-diol, 5-Cholestene-3beta,25-diol, 25-OHC.

What is the molecular formula and molecular weight of 25-Hydroxy Cholesterol?

25-Hydroxy Cholesterol has the molecular formula C27H46O2 and a molecular weight of 402.7 g/mol. Its IUPAC name is (3S,8S,9S,10R,13R,14S,17R)-17-[(2R)-6-hydroxy-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol.

What is 25-Hydroxy Cholesterol used for?

25-Hydroxy Cholesterol is supplied as a characterised reference material related to Cholesterol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 25-Hydroxy Cholesterol can I order?

We supply 25-Hydroxy Cholesterol in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 25-Hydroxy Cholesterol?

Yes. Every lot of 25-Hydroxy Cholesterol is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 25-Hydroxy Cholesterol be shipped internationally?

Yes. 25-Hydroxy Cholesterol is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.