Lofexidine Hydrochloride

Name: Lofexidine Hydrochloride
Brand: Vaqora Chemicals
SKU: VQ-048917

About Lofexidine Hydrochloride

Lofexidine Hydrochloride is a high-purity reference standard of Lofexidine carrying the CAS registry number 21498-08-8. Its molecular formula is C11H13Cl3N2O and its molecular weight is 295.6 g/mol. Alternative names: LOFEXIDINE HCl and MDL 14,042.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Danger” with 1 hazard statement. Review the Safety Data Sheet before use.

Laboratories use this Lofexidine standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Lofexidine Hydrochloride in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Lofexidine

View every impurity, metabolite and intermediate we list for Lofexidine.

Lofexidine impurities

Specifications & identifiers

Chemical identifiers
Product name	Lofexidine Hydrochloride
Catalogue No.	VQ-048917
CAS Number	21498-08-8
IUPAC name	2-[1-(2,6-dichlorophenoxy)ethyl]-4,5-dihydro-1H-imidazole;hydrochloride
Molecular formula	C₁₁H₁₃Cl₃N₂O
Molecular weight	295.6 g/mol
Exact mass	294.0093
Grade	Reference Standard
HSN code	38229090
InChIKey	DWWHMKBNNNZGHF-UHFFFAOYSA-N
SMILES	CC(C1=NCCN1)OC2=C(C=CC=C2Cl)Cl.Cl
PubChem CID	30667

Physical properties
Physical form	Solid
H-bond donors / acceptors	2 / 2
TPSA	33.6 Å²
Synonyms	LOFEXIDINE HCl, MDL 14,042, 2-[1-(2,6-dichlorophenoxy)ethyl]-4,5-dihydro-1H-imidazole hydrochloride, 2-(1-(2,6-Dichlorophenoxy)ethyl)-4,5-dihydro-1H-imidazole hydrochloride, 1H-Imidazole, 2-(1-(2,6-dichlorophenoxy)ethyl)-4,5-dihydro-, monohydrochloride, 2-(1-(2,6-Dichlorophenoxy)ethyl)-2-imidazoline monohydrochloride, lofexidine monohydrochloride, 2-[1-(2,6-Dichlorophenoxy)ethyl]-2-imidazoline monohydrochloride, Lofexidine mono-hydrochloride, Lofetensin, 1H-Imidazole, 2-[1-(2,6-dichlorophenoxy)ethyl]-4,5-dihydro-,monohydrochloride

Safety & hazard information (GHS)

Toxic

Signal word: Danger

Hazard statements

H301Toxic if swallowed

Precautionary statements: P264, P270, P301 + P316, P321, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Lofexidine Hydrochloride?

The CAS Registry Number of Lofexidine Hydrochloride is 21498-08-8. It is also known as LOFEXIDINE HCl, MDL 14,042, 2-[1-(2,6-dichlorophenoxy)ethyl]-4,5-dihydro-1H-imidazole hydrochloride.

What is the molecular formula and molecular weight of Lofexidine Hydrochloride?

Lofexidine Hydrochloride has the molecular formula C11H13Cl3N2O and a molecular weight of 295.6 g/mol.

What is Lofexidine Hydrochloride used for?

Lofexidine Hydrochloride is supplied as a characterised reference material related to Lofexidine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Lofexidine Hydrochloride can I order?

We supply Lofexidine Hydrochloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Lofexidine Hydrochloride?

Yes. Every lot of Lofexidine Hydrochloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Lofexidine Hydrochloride be shipped internationally?

Yes. Lofexidine Hydrochloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.