1-Methyl-3-nitrophthalate

Name: 1-Methyl-3-nitrophthalate
Brand: Vaqora Chemicals
SKU: VQ-049425

About 1-Methyl-3-nitrophthalate

1-Methyl-3-nitrophthalate (CAS 21606-04-2) is a process intermediate or related compound of Candesartan offered by Vaqora Chemicals. With the molecular formula C9H7NO6, it has a molar mass of 225.15 g/mol. The IUPAC name is 2-methoxycarbonyl-6-nitrobenzoic acid. Common synonyms include Methyl-2-carboxy-3-nitrobenzoate and 2-(methoxycarbonyl)-6-nitrobenzoic acid.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 1 hazard statement. Review the Safety Data Sheet before use.

Process chemists and analysts use it when developing synthetic routes to Candesartan, tracking process-related impurities and validating analytical methods. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Candesartan

View every impurity, metabolite and intermediate we list for Candesartan.

Candesartan impurities

Specifications & identifiers

Chemical identifiers
Product name	1-Methyl-3-nitrophthalate
Catalogue No.	VQ-049425
CAS Number	21606-04-2
IUPAC name	2-methoxycarbonyl-6-nitrobenzoic acid
Molecular formula	C₉H₇NO₆
Molecular weight	225.15 g/mol
Exact mass	225.0273
InChIKey	DJMQLZPEBHSABD-UHFFFAOYSA-N
SMILES	COC(=O)C1=C(C(=CC=C1)[N+](=O)[O-])C(=O)O
PubChem CID	4399477

Physical properties
Physical form	Solid
LogP (XLogP3)	1.1
H-bond donors / acceptors	1 / 6
TPSA	109 Å²
Synonyms	Methyl-2-carboxy-3-nitrobenzoate, 2-(methoxycarbonyl)-6-nitrobenzoic acid, Methyl 2-carboxy-3-nitrobenzoate, 2-(Methoxycarbonyl)-6-nitrobenzoicAcid, 1,2-Benzenedicarboxylic acid, 3-nitro-, 1-methyl ester, 3-Nitro-1,2-Benzenedicarboxylic Acid Monomethyl Ester, 3-Nitro-phthalic acid 1-Methyl ester, 2-methoxycarbonyl-6-nitro-benzoic Acid, 2-methoxycarb, 6-(methoxycarbonyl)-2-nitrobenzoic acid, 3-Nitrophthalic acid 1-methyl ester, 1-Methyl 3-nitro-1,2-benzenedicarboxylate

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 1-Methyl-3-nitrophthalate?

The CAS Registry Number of 1-Methyl-3-nitrophthalate is 21606-04-2. It is also known as Methyl-2-carboxy-3-nitrobenzoate, 2-(methoxycarbonyl)-6-nitrobenzoic acid, Methyl 2-carboxy-3-nitrobenzoate.

What is the molecular formula and molecular weight of 1-Methyl-3-nitrophthalate?

1-Methyl-3-nitrophthalate has the molecular formula C9H7NO6 and a molecular weight of 225.15 g/mol. Its IUPAC name is 2-methoxycarbonyl-6-nitrobenzoic acid.

What is 1-Methyl-3-nitrophthalate used for?

1-Methyl-3-nitrophthalate is supplied as a characterised reference material related to Candesartan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 1-Methyl-3-nitrophthalate can I order?

We supply 1-Methyl-3-nitrophthalate, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 1-Methyl-3-nitrophthalate?

Yes. Every lot of 1-Methyl-3-nitrophthalate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 1-Methyl-3-nitrophthalate be shipped internationally?

Yes. 1-Methyl-3-nitrophthalate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.