(S)-3-(Boc-amino)piperidine

Name: (S)-3-(Boc-amino)piperidine
Brand: Vaqora Chemicals
SKU: VQ-026472

About (S)-3-(Boc-amino)piperidine

Listed under CAS 216854-23-8, (S)-3-(Boc-amino)piperidine is an impurity of Linagliptin available from Vaqora Chemicals. The compound has the formula C10H20N2O2, corresponding to a molecular weight of 200.28 g/mol. Systematically, it is named tert-butyl N-[(3S)-piperidin-3-yl]carbamate. Common synonyms include tert-butyl N-((3S)-piperidin-3-yl)carbamate and (S)-3-N-Boc-aminopiperidine.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Danger” with 4 hazard statements. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Linagliptin to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, (S)-3-(Boc-amino)piperidine is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Linagliptin

View every impurity, metabolite and intermediate we list for Linagliptin.

Linagliptin impurities

Specifications & identifiers

Chemical identifiers
Product name	(S)-3-(Boc-amino)piperidine
Catalogue No.	VQ-026472
CAS Number	216854-23-8
IUPAC name	tert-butyl N-[(3S)-piperidin-3-yl]carbamate
Molecular formula	C₁₀H₂₀N₂O₂
Molecular weight	200.28 g/mol
Exact mass	200.1525
Grade	Reference Standard
HSN code	38229090
InChIKey	WUOQXNWMYLFAHT-QMMMGPOBSA-N
SMILES	CC(C)(C)OC(=O)N[C@H]1CCCNC1
PubChem CID	1514171

Physical properties
Physical form	Solid
LogP (XLogP3)	1.1
H-bond donors / acceptors	2 / 3
TPSA	50.4 Å²
Synonyms	tert-butyl N-((3S)-piperidin-3-yl)carbamate, (S)-3-N-Boc-aminopiperidine, (S)-tert-butyl piperidin-3-ylcarbamate, (S)-3-(Tert-Butoxycarbonylamino)Piperidine, (S)-3-(tert-butoxycarbonylamino)piperdine, (3S)-(-)-3-(tert-butoxycarbonylamino)piperidine, (3s)-3-aminopiperidine, 3-boc protected, (s)-3-n-boc-amino piperidine, 3-(Boc-amino)piperidine, (S)-, CS-B0850

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Signal word: Danger

Hazard statements

H315Causes skin irritation
H318Causes serious eye damage
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P305 + P354 + P338, P317, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (S)-3-(Boc-amino)piperidine?

The CAS Registry Number of (S)-3-(Boc-amino)piperidine is 216854-23-8. It is also known as tert-butyl N-((3S)-piperidin-3-yl)carbamate, (S)-3-N-Boc-aminopiperidine, (S)-tert-butyl piperidin-3-ylcarbamate.

What is the molecular formula and molecular weight of (S)-3-(Boc-amino)piperidine?

(S)-3-(Boc-amino)piperidine has the molecular formula C10H20N2O2 and a molecular weight of 200.28 g/mol. Its IUPAC name is tert-butyl N-[(3S)-piperidin-3-yl]carbamate.

What is (S)-3-(Boc-amino)piperidine used for?

(S)-3-(Boc-amino)piperidine is supplied as a characterised reference material related to Linagliptin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (S)-3-(Boc-amino)piperidine can I order?

We supply (S)-3-(Boc-amino)piperidine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (S)-3-(Boc-amino)piperidine?

Yes. Every lot of (S)-3-(Boc-amino)piperidine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (S)-3-(Boc-amino)piperidine be shipped internationally?

Yes. (S)-3-(Boc-amino)piperidine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.