ThioLinezolid

About ThioLinezolid

ThioLinezolid is an impurity of Linezolid carrying the CAS registry number 216868-57-4. Formula C16H20FN3O3S, molecular weight 353.4 g/mol. The IUPAC name is N-[[(5S)-3-(3-fluoro-4-morpholin-4-ylphenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl]ethanethioamide. It is also known as Deacetyl Linezolid Thioacetamide.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

This Linezolid impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, ThioLinezolid is dispatched with a Certificate of Analysis (COA) to destinations worldwide. A Safety Data Sheet (SDS) and technical specifications are available on request.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Linezolid

View every impurity, metabolite and intermediate we list for Linezolid.

Linezolid impurities

Specifications & identifiers

Chemical identifiers
Product name	ThioLinezolid
Catalogue No.	VQ-026490
CAS Number	216868-57-4
IUPAC name	N-[[(5S)-3-(3-fluoro-4-morpholin-4-ylphenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl]ethanethioamide
Molecular formula	C₁₆H₂₀FN₃O₃S
Molecular weight	353.4 g/mol
Exact mass	353.1209
Grade	Reference Standard
HSN code	38229090
InChIKey	ARKKSPJWSZIEQK-ZDUSSCGKSA-N
SMILES	CC(=S)NC[C@H]1CN(C(=O)O1)C2=CC(=C(C=C2)N3CCOCC3)F
PubChem CID	12040041

Physical properties
Physical form	Solid
LogP (XLogP3)	1.3
H-bond donors / acceptors	1 / 6
TPSA	86.1 Å²
Synonyms	Deacetyl Linezolid Thioacetamide, (S)-N-((3-(3-Fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl)ethanethioamide, (s)-n-{[3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl]methyl}thioacetamide, (S)-N-((3-(3-Fluoro-4-morpholino phenyl)-2-oxooxazolidin-5-yl)methyl) thioacetamide, (S)-N-[[3-(3-Fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl]methyl]thioacetamide, (S)-N-{[3-(3-Fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl]methyl} thioacetamide, (S)-N -[[3-[3-Fluoro-4-(4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]thioacetamide, (S)-N-[[3-[3-Fluoro-4-(4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]thioacetamide

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of ThioLinezolid?

The CAS Registry Number of ThioLinezolid is 216868-57-4. It is also known as Deacetyl Linezolid Thioacetamide, (S)-N-((3-(3-Fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl)ethanethioamide, (s)-n-{[3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl]methyl}thioacetamide.

What is the molecular formula and molecular weight of ThioLinezolid?

ThioLinezolid has the molecular formula C16H20FN3O3S and a molecular weight of 353.4 g/mol. Its IUPAC name is N-[[(5S)-3-(3-fluoro-4-morpholin-4-ylphenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl]ethanethioamide.

What is ThioLinezolid used for?

ThioLinezolid is supplied as a characterised reference material related to Linezolid. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of ThioLinezolid can I order?

We supply ThioLinezolid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with ThioLinezolid?

Yes. Every lot of ThioLinezolid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can ThioLinezolid be shipped internationally?

Yes. We export ThioLinezolid worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.