Etifoxine

Name: Etifoxine
Brand: Vaqora Chemicals
SKU: VQ-030616

About Etifoxine

Listed under CAS 21715-46-8, Etifoxine is a high-purity reference standard of Etifoxine available from Vaqora Chemicals. Its molecular formula is C17H17ClN2O and its molecular weight is 300.8 g/mol. Its systematic (IUPAC) name is 6-chloro-N-ethyl-4-methyl-4-phenyl-1H-3,1-benzoxazin-2-imine. It is also known as Etifoxin or Etafenoxine.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Laboratories use this Etifoxine standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Etifoxine

View every impurity, metabolite and intermediate we list for Etifoxine.

Etifoxine impurities

Specifications & identifiers

Chemical identifiers
Product name	Etifoxine
Catalogue No.	VQ-030616
CAS Number	21715-46-8
IUPAC name	6-chloro-N-ethyl-4-methyl-4-phenyl-1H-3,1-benzoxazin-2-imine
Molecular formula	C₁₇H₁₇ClN₂O
Molecular weight	300.8 g/mol
Exact mass	300.1029
Grade	Reference Standard
HSN code	38229090
InChIKey	IBYCYJFUEJQSMK-UHFFFAOYSA-N
SMILES	CCN=C1NC2=C(C=C(C=C2)Cl)C(O1)(C)C3=CC=CC=C3
PubChem CID	135413553

Physical properties
Physical form	Solid
LogP (XLogP3)	4.1
H-bond donors / acceptors	1 / 2
TPSA	33.6 Å²
Synonyms	Etifoxin, Etafenoxine, 6-chloro-N-ethyl-4-methyl-4-phenyl-2,4-dihydro-1H-3,1-benzoxazin-2-imine, etafenoxine hydrochloride, 2-ethylamino-6-chloro-4-methyl-4-phenyl-4H-3,1-benzoxazine, HOE 36-801, 6-chloro-N-ethyl-4-methyl-4-phenyl-3,1-benzoxazin-2-amine, 6-Chloro-N-ethyl-4-methyl-4-phenyl-4H-benzo[d][1,3]oxazin-2-amine, 6-chloro-N-ethyl-4-methyl-4-phenyl-4H-3,1-benzoxazin-2-amine, 6-Chloro-2-ethylamino-4-methyl-4-phenyl-4H-3,1-benzoxazine, 6-Chloro-2-(ethylamino)-4-methyl-4-phenyl-4H-3,1-benzoxazine, 4H-3,1-Benzoxazin-2-amine, 6-chloro-N-ethyl-4-methyl-4-phenyl-

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H401Toxic to aquatic life

Precautionary statements: P264, P270, P273, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Etifoxine?

The CAS Registry Number of Etifoxine is 21715-46-8. It is also known as Etifoxin, Etafenoxine, 6-chloro-N-ethyl-4-methyl-4-phenyl-2,4-dihydro-1H-3,1-benzoxazin-2-imine.

What is the molecular formula and molecular weight of Etifoxine?

Etifoxine has the molecular formula C17H17ClN2O and a molecular weight of 300.8 g/mol. Its IUPAC name is 6-chloro-N-ethyl-4-methyl-4-phenyl-1H-3,1-benzoxazin-2-imine.

What is Etifoxine used for?

Etifoxine is supplied as a characterised reference material related to Etifoxine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Etifoxine can I order?

We supply Etifoxine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Etifoxine?

Yes. Every lot of Etifoxine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Etifoxine be shipped internationally?

Yes. Etifoxine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.