3-(4-(Methylamino)-1-oxoisoindolin-2-yl)piper… 2197421-58-0

About 3-(4-(Methylamino)-1-oxoisoindolin-2-yl)piperidine-2,6-dione

3-(4-(Methylamino)-1-oxoisoindolin-2-yl)piperidine-2,6-dione is an impurity of Lenalidomide carrying the CAS registry number 2197421-58-0. Formula C14H15N3O3, molecular weight 273.29 g/mol. The IUPAC name is 3-[7-(methylamino)-3-oxo-1H-isoindol-2-yl]piperidine-2,6-dione. It is also known as N-Methyl Lenalidomide.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

This Lenalidomide impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Lenalidomide

View every impurity, metabolite and intermediate we list for Lenalidomide.

Lenalidomide impurities

Specifications & identifiers

Chemical identifiers
Product name	3-(4-(Methylamino)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
Catalogue No.	VQ-031477
CAS Number	2197421-58-0
IUPAC name	3-[7-(methylamino)-3-oxo-1H-isoindol-2-yl]piperidine-2,6-dione
Molecular formula	C₁₄H₁₅N₃O₃
Molecular weight	273.29 g/mol
Exact mass	273.1113
Grade	Reference Standard
HSN code	38229090
InChIKey	OWRWODIJEBVKPL-UHFFFAOYSA-N
SMILES	CNC1=CC=CC2=C1CN(C2=O)C3CCC(=O)NC3=O
PubChem CID	67026754

Physical properties
Physical form	Solid
LogP (XLogP3)	0.2
H-bond donors / acceptors	2 / 4
TPSA	78.5 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 3-(4-(Methylamino)-1-oxoisoindolin-2-yl)piperidine-2,6-dione?

The CAS Registry Number of 3-(4-(Methylamino)-1-oxoisoindolin-2-yl)piperidine-2,6-dione is 2197421-58-0. It is also known as N-Methyl Lenalidomide, 2,6-Piperidinedione, 3-[1,3-dihydro-4-(methylamino)-1-oxo-2H-isoindol-2-yl]-, 3-[1,3-Dihydro-4-(methylamino)-1-oxo-2H-isoindol-2-yl]-2,6-piperidinedione.

What is the molecular formula and molecular weight of 3-(4-(Methylamino)-1-oxoisoindolin-2-yl)piperidine-2,6-dione?

3-(4-(Methylamino)-1-oxoisoindolin-2-yl)piperidine-2,6-dione has the molecular formula C14H15N3O3 and a molecular weight of 273.29 g/mol. Its IUPAC name is 3-[7-(methylamino)-3-oxo-1H-isoindol-2-yl]piperidine-2,6-dione.

What is 3-(4-(Methylamino)-1-oxoisoindolin-2-yl)piperidine-2,6-dione used for?

3-(4-(Methylamino)-1-oxoisoindolin-2-yl)piperidine-2,6-dione is supplied as a characterised reference material related to Lenalidomide. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 3-(4-(Methylamino)-1-oxoisoindolin-2-yl)piperidine-2,6-dione can I order?

We supply 3-(4-(Methylamino)-1-oxoisoindolin-2-yl)piperidine-2,6-dione in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 3-(4-(Methylamino)-1-oxoisoindolin-2-yl)piperidine-2,6-dione?

Yes. Every lot of 3-(4-(Methylamino)-1-oxoisoindolin-2-yl)piperidine-2,6-dione is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 3-(4-(Methylamino)-1-oxoisoindolin-2-yl)piperidine-2,6-dione be shipped internationally?

Yes. We export 3-(4-(Methylamino)-1-oxoisoindolin-2-yl)piperidine-2,6-dione worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.