(R)-3-(p-toluenesulfonyl) oxytetrahydrofuran 219823-47-9

Name: (R)-3-(p-toluenesulfonyl) oxytetrahydrofuran
Brand: Vaqora Chemicals
SKU: VQ-012782

About (R)-3-(p-toluenesulfonyl) oxytetrahydrofuran

(R)-3-(p-toluenesulfonyl) oxytetrahydrofuran (CAS 219823-47-9) is a process intermediate or related compound of Empagliflozin offered by Vaqora Chemicals. Formula C11H14O4S, molecular weight 242.29 g/mol. Its systematic (IUPAC) name is [(3R)-oxolan-3-yl] 4-methylbenzenesulfonate. Common synonyms include (R)-(-)-3-tetrahydrofuranyl tosylate and (3R)-Oxolan-3-yl 4-methylbenzene-1-sulfonate.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Warning” with 4 hazard statements. Review the Safety Data Sheet before use.

It is a process intermediate or related compound in the synthesis of Empagliflozin, useful for route development, impurity fate-and-purge studies and analytical method development. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies (R)-3-(p-toluenesulfonyl) oxytetrahydrofuran in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Empagliflozin

View every impurity, metabolite and intermediate we list for Empagliflozin.

Empagliflozin impurities

Specifications & identifiers

Chemical identifiers
Product name	(R)-3-(p-toluenesulfonyl) oxytetrahydrofuran
Catalogue No.	VQ-012782
CAS Number	219823-47-9
IUPAC name	[(3R)-oxolan-3-yl] 4-methylbenzenesulfonate
Molecular formula	C₁₁H₁₄O₄S
Molecular weight	242.29 g/mol
Exact mass	242.0613
Grade	Reference Standard
InChIKey	WWCNXHYRAKUQDB-SNVBAGLBSA-N
SMILES	CC1=CC=C(C=C1)S(=O)(=O)O[C@@H]2CCOC2
PubChem CID	11149197

Physical properties
Physical form	Solid
LogP (XLogP3)	1.6
H-bond donors / acceptors	0 / 4
TPSA	61 Å²
Synonyms	(3R)-Tetrahydrofuran-3-yl 4-Methylbenzenesulfonate, (R)-(-)-3-tetrahydrofuranyl tosylate, (3R)-Tetrahydro-3-furanol 4-Methylbenzenesulfonate, (R)-Toluene-4-sulfonic Acid Tetrahydrofuran-3-yl Ester, (3R)-Oxolan-3-yl 4-methylbenzene-1-sulfonate, 4-Methylbenzenesulfonic acid (3R)-oxolan-3-yl ester, Tetrahydrofuran-3-yl 4-methylbenzenesulfonate, (3R)-, 3-Furanol, tetrahydro-, 4-methylbenzenesulfonate, (3R)-, 3-Furanol, tetrahydro-, 3-(4-methylbenzenesulfonate), (3R)-, (R)-tetrahydrofuran-3-yl 4-methylbenzenesulfonate, R)-3-(p-toluenesulfonyl) oxytetrahydrofuran, (R)-tetrahydrofuran-3-yl4-methylbenzenesulfonate

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (R)-3-(p-toluenesulfonyl) oxytetrahydrofuran?

The CAS Registry Number of (R)-3-(p-toluenesulfonyl) oxytetrahydrofuran is 219823-47-9. It is also known as (3R)-Tetrahydrofuran-3-yl 4-Methylbenzenesulfonate, (R)-(-)-3-tetrahydrofuranyl tosylate, (3R)-Tetrahydro-3-furanol 4-Methylbenzenesulfonate.

What is the molecular formula and molecular weight of (R)-3-(p-toluenesulfonyl) oxytetrahydrofuran?

(R)-3-(p-toluenesulfonyl) oxytetrahydrofuran has the molecular formula C11H14O4S and a molecular weight of 242.29 g/mol. Its IUPAC name is [(3R)-oxolan-3-yl] 4-methylbenzenesulfonate.

What is (R)-3-(p-toluenesulfonyl) oxytetrahydrofuran used for?

(R)-3-(p-toluenesulfonyl) oxytetrahydrofuran is supplied as a characterised reference material related to Empagliflozin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (R)-3-(p-toluenesulfonyl) oxytetrahydrofuran can I order?

We supply (R)-3-(p-toluenesulfonyl) oxytetrahydrofuran in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (R)-3-(p-toluenesulfonyl) oxytetrahydrofuran?

Yes. Every lot of (R)-3-(p-toluenesulfonyl) oxytetrahydrofuran is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (R)-3-(p-toluenesulfonyl) oxytetrahydrofuran be shipped internationally?

Yes. (R)-3-(p-toluenesulfonyl) oxytetrahydrofuran is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.