Ixabepilone

Name: Ixabepilone
Brand: Vaqora Chemicals
SKU: VQ-031353

About Ixabepilone

Listed under CAS 219989-84-1, Ixabepilone is a high-purity reference standard of Ixabepilone available from Vaqora Chemicals. With the molecular formula C27H42N2O5S, it has a molar mass of 506.7 g/mol. It is also known as Azaepothilone B or Aza-epothilone B.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

As a reference sample of Ixabepilone, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Ixabepilone

View every impurity, metabolite and intermediate we list for Ixabepilone.

Ixabepilone impurities

Specifications & identifiers

Chemical identifiers
Product name	Ixabepilone
Catalogue No.	VQ-031353
CAS Number	219989-84-1
IUPAC name	(1S,3S,7S,10R,11S,12S,16R)-7,11-dihydroxy-8,8,10,12,16-pentamethyl-3-[(E)-1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-17-oxa-4-azabicyclo[14.1.0]heptadecane-5,9-dione
Molecular formula	C₂₇H₄₂N₂O₅S
Molecular weight	506.7 g/mol
Exact mass	506.2814
Grade	Reference Standard
HSN code	38229090
InChIKey	FABUFPQFXZVHFB-PVYNADRNSA-N
SMILES	C[C@H]1CCC[C@@]2([C@@H](O2)C[C@H](NC(=O)C[C@@H](C(C(=O)[C@@H]([C@H]1O)C)(C)C)O)/C(=C/C3=CSC(=N3)C)/C)C
PubChem CID	6445540

Physical properties
Physical form	Solid
LogP (XLogP3)	3.6
H-bond donors / acceptors	3 / 7
TPSA	140 Å²
Synonyms	Azaepothilone B, Aza-epothilone B, Ixempra kit, Azi-epothilone B, Ixempra (TM), 16-Aza-epothilone B, EX-A1245

Safety & hazard information (GHS)

Toxic

Harmful / irritant

Health hazard

Environmental hazard

Signal word: Danger

Hazard statements

H300Fatal if swallowed
H301Toxic if swallowed
H317May cause an allergic skin reaction
H341Suspected of causing genetic defects
H360May damage fertility or the unborn child
H361Suspected of damaging fertility or the unborn child
H372Causes damage to organs through prolonged or repeated exposure
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects

Precautionary statements: P203, P260, P261, P264, P270, P272, P273, P280, P301 + P316, P302 + P352, P318, P319, P321, P330, P333 + P317, P362 + P364, P391, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Ixabepilone?

The CAS Registry Number of Ixabepilone is 219989-84-1. It is also known as Azaepothilone B, Aza-epothilone B, Ixempra kit.

What is the molecular formula and molecular weight of Ixabepilone?

Ixabepilone has the molecular formula C27H42N2O5S and a molecular weight of 506.7 g/mol.

What is Ixabepilone used for?

Ixabepilone is supplied as a characterised reference material related to Ixabepilone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ixabepilone can I order?

We supply Ixabepilone in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ixabepilone?

Yes. Every lot of Ixabepilone is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ixabepilone be shipped internationally?

Yes. Ixabepilone is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.