5-Methoxy-2-[[(4-chloro-3,5-dimethylpyridin-2… 220757-74-4

Name: 5-Methoxy-2-[[(4-chloro-3,5-dimethylpyridin-2-yl)methyl]sulphanyl]-1H-benzimidazole
Brand: Vaqora Chemicals
SKU: VQ-027015

About 5-Methoxy-2-[[(4-chloro-3,5-dimethylpyridin-2-yl)methyl]sulphanyl]-1H-benzimidazole

Listed under CAS 220757-74-4, 5-Methoxy-2-[[(4-chloro-3,5-dimethylpyridin-2-yl)methyl]sulphanyl]-1H-benzimidazole is an impurity of Omeprazole available from Vaqora Chemicals. The compound has the formula C16H16ClN3OS, corresponding to a molecular weight of 333.8 g/mol. Its systematic (IUPAC) name is 2-[(4-chloro-3,5-dimethyl-2-pyridinyl)methylsulfanyl]-6-methoxy-1H-benzimidazole. Common synonyms include 4-Desmethoxy-4-chloro Omeprazole Sulfide and Omeprazole 4-chloro Analog.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Warning” with 1 hazard statement. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Omeprazole to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 5-Methoxy-2-[[(4-chloro-3,5-dimethylpyridin-2-yl)methyl]sulphanyl]-1H-benzimidazole is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Omeprazole

View every impurity, metabolite and intermediate we list for Omeprazole.

Omeprazole impurities

Specifications & identifiers

Chemical identifiers
Product name	5-Methoxy-2-[[(4-chloro-3,5-dimethylpyridin-2-yl)methyl]sulphanyl]-1H-benzimidazole
Catalogue No.	VQ-027015
CAS Number	220757-74-4
IUPAC name	2-[(4-chloro-3,5-dimethyl-2-pyridinyl)methylsulfanyl]-6-methoxy-1H-benzimidazole
Molecular formula	C₁₆H₁₆ClN₃OS
Molecular weight	333.8 g/mol
Exact mass	333.0703
Grade	Reference Standard
HSN code	38229090
InChIKey	UPVARCHBWKDWRW-UHFFFAOYSA-N
SMILES	CC1=CN=C(C(=C1Cl)C)CSC2=NC3=C(N2)C=C(C=C3)OC
PubChem CID	9797740

Physical properties
Physical form	Solid
LogP (XLogP3)	4.2
H-bond donors / acceptors	1 / 4
TPSA	76.1 Å²
Synonyms	4-Desmethoxy-4-chloro Omeprazole Sulfide, Omeprazole 4-chloro Analog, Omeprazole 4-Desmethoxy-4-Chloro Sulfide Analog, 2-(((4-Chloro-3,5-dimethylpyridin-2-yl)methyl)thio)-6-methoxy-1H-benzo[d]imidazole, 2-[(4-chloro-3,5-dimethylpyridin-2-yl)methylsulfanyl]-6-methoxy-1H-benzimidazole, 2-(((4-chloro-3,5-dimethylpyridin-2-yl)methyl)thio)-5-methoxy-1H-benzo[d]imidazole, 2-[[(4-Chloro-3,5-dimethyl-2-pyridinyl)methyl]thio]-6-methoxy-1H-benzimidazole, 1H-Benzimidazole, 2-[[(4-chloro-3,5-dimethyl-2-pyridinyl)methyl]thio]-6-methoxy-, 5-methoxy-2-{[(4-chloro-3,5-dimethyl-pyridin-2-yl)methyl]thio}-1H-benzimidazole, 2-[[(4-Chloro-3,5-dimethyl-2-pyridyl)methyl]thio]-6-methoxybenzimidazole, 2-[(4-Chloro-3,5-dimethyl-2-pyridinyl)methylthio]-6-methoxy-1H-benzimidazole

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 5-Methoxy-2-[[(4-chloro-3,5-dimethylpyridin-2-yl)methyl]sulphanyl]-1H-benzimidazole?

The CAS Registry Number of 5-Methoxy-2-[[(4-chloro-3,5-dimethylpyridin-2-yl)methyl]sulphanyl]-1H-benzimidazole is 220757-74-4. It is also known as 4-Desmethoxy-4-chloro Omeprazole Sulfide, Omeprazole 4-chloro Analog, Omeprazole 4-Desmethoxy-4-Chloro Sulfide Analog.

What is the molecular formula and molecular weight of 5-Methoxy-2-[[(4-chloro-3,5-dimethylpyridin-2-yl)methyl]sulphanyl]-1H-benzimidazole?

5-Methoxy-2-[[(4-chloro-3,5-dimethylpyridin-2-yl)methyl]sulphanyl]-1H-benzimidazole has the molecular formula C16H16ClN3OS and a molecular weight of 333.8 g/mol. Its IUPAC name is 2-[(4-chloro-3,5-dimethyl-2-pyridinyl)methylsulfanyl]-6-methoxy-1H-benzimidazole.

What is 5-Methoxy-2-[[(4-chloro-3,5-dimethylpyridin-2-yl)methyl]sulphanyl]-1H-benzimidazole used for?

5-Methoxy-2-[[(4-chloro-3,5-dimethylpyridin-2-yl)methyl]sulphanyl]-1H-benzimidazole is supplied as a characterised reference material related to Omeprazole. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 5-Methoxy-2-[[(4-chloro-3,5-dimethylpyridin-2-yl)methyl]sulphanyl]-1H-benzimidazole can I order?

We supply 5-Methoxy-2-[[(4-chloro-3,5-dimethylpyridin-2-yl)methyl]sulphanyl]-1H-benzimidazole in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 5-Methoxy-2-[[(4-chloro-3,5-dimethylpyridin-2-yl)methyl]sulphanyl]-1H-benzimidazole?

Yes. Every lot of 5-Methoxy-2-[[(4-chloro-3,5-dimethylpyridin-2-yl)methyl]sulphanyl]-1H-benzimidazole is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 5-Methoxy-2-[[(4-chloro-3,5-dimethylpyridin-2-yl)methyl]sulphanyl]-1H-benzimidazole be shipped internationally?

Yes. 5-Methoxy-2-[[(4-chloro-3,5-dimethylpyridin-2-yl)methyl]sulphanyl]-1H-benzimidazole is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.