Bis(2-nitrophenyl) Sulfide

About Bis(2-nitrophenyl) Sulfide

Bis(2-nitrophenyl) Sulfide is an impurity of Dapsone carrying the CAS registry number 22100-66-9. With the molecular formula C12H8N2O4S, it has a molar mass of 276.27 g/mol. Its systematic (IUPAC) name is 1-nitro-2-(2-nitrophenyl)sulfanylbenzene. Alternative names: Bis(2-nitrophenyl)sulfane and 1-nitro-2-[(2-nitrophenyl)sulfanyl]benzene.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

As a characterised impurity of Dapsone, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Dapsone

View every impurity, metabolite and intermediate we list for Dapsone.

Dapsone impurities

Specifications & identifiers

Chemical identifiers
Product name	Bis(2-nitrophenyl) Sulfide
Catalogue No.	VQ-036542
CAS Number	22100-66-9
IUPAC name	1-nitro-2-(2-nitrophenyl)sulfanylbenzene
Molecular formula	C₁₂H₈N₂O₄S
Molecular weight	276.27 g/mol
Exact mass	276.0205
Grade	Reference Standard
HSN code	38229090
InChIKey	MXWVNAOIXKIIJK-UHFFFAOYSA-N
SMILES	C1=CC=C(C(=C1)[N+](=O)[O-])SC2=CC=CC=C2[N+](=O)[O-]
PubChem CID	363892

Physical properties
Physical form	Solid
LogP (XLogP3)	3.6
H-bond donors / acceptors	0 / 5
TPSA	117 Å²
Synonyms	Bis(2-nitrophenyl)sulfane, 1-nitro-2-[(2-nitrophenyl)sulfanyl]benzene, 1,1'-sulfanediylbis(2-nitrobenzene), 1-nitro-2-(2-nitrophenyl)sulfanyl-benzene, Bisnitrophenylsulfide, nitrophenyl thioether, Bis(2NO2Ph)S, 22'-Nitrodiphenylfulfide, Di-2-Nitrophenylthioether, 2,2'-Dinitrodiphenylsulfide, 1,1'-Thiobis[2-nitrobenzene]

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H319Causes serious eye irritation

Precautionary statements: P264 + P265, P280, P305 + P351 + P338, P337 + P317

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Bis(2-nitrophenyl) Sulfide?

The CAS Registry Number of Bis(2-nitrophenyl) Sulfide is 22100-66-9. It is also known as Bis(2-nitrophenyl)sulfane, 1-nitro-2-[(2-nitrophenyl)sulfanyl]benzene, 1,1'-sulfanediylbis(2-nitrobenzene).

What is the molecular formula and molecular weight of Bis(2-nitrophenyl) Sulfide?

Bis(2-nitrophenyl) Sulfide has the molecular formula C12H8N2O4S and a molecular weight of 276.27 g/mol. Its IUPAC name is 1-nitro-2-(2-nitrophenyl)sulfanylbenzene.

What is Bis(2-nitrophenyl) Sulfide used for?

Bis(2-nitrophenyl) Sulfide is supplied as a characterised reference material related to Dapsone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Bis(2-nitrophenyl) Sulfide can I order?

We supply Bis(2-nitrophenyl) Sulfide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Bis(2-nitrophenyl) Sulfide?

Yes. Every lot of Bis(2-nitrophenyl) Sulfide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Bis(2-nitrophenyl) Sulfide be shipped internationally?

Yes. Bis(2-nitrophenyl) Sulfide is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.