Clobazam Impurity A

About Clobazam Impurity A

Clobazam Impurity A is an impurity of Clobazam carrying the CAS registry number 22316-55-8. Formula C15H11ClN2O2, molecular weight 286.71 g/mol. Its systematic (IUPAC) name is 7-chloro-5-phenyl-1H-1,5-benzodiazepine-2,4-dione. It is also known as Desmethylclobazam or N-Desmethyl Clobazam.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

As a characterised impurity of Clobazam, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Clobazam

View every impurity, metabolite and intermediate we list for Clobazam.

Clobazam impurities

Specifications & identifiers

Chemical identifiers
Product name	Clobazam Impurity A
Catalogue No.	VQ-004654
CAS Number	22316-55-8
IUPAC name	7-chloro-5-phenyl-1H-1,5-benzodiazepine-2,4-dione
Molecular formula	C₁₅H₁₁ClN₂O₂
Molecular weight	286.71 g/mol
Exact mass	286.0509
Grade	Reference Standard
HSN code	38229090
InChIKey	RRTVVRIFVKKTJK-UHFFFAOYSA-N
SMILES	C1C(=O)NC2=C(C=C(C=C2)Cl)N(C1=O)C3=CC=CC=C3
PubChem CID	89657

Physical properties
Physical form	Solid
LogP (XLogP3)	1.9
H-bond donors / acceptors	1 / 2
TPSA	49.4 Å²
Synonyms	Desmethylclobazam, 8-Chloro-1-phenyl-1H-1,5-benzodiazepine-2,4(3H,5H)-dione, 7-Chloro-5-phenyl-1,5-dihydro-3H-1,5-benzodiazepine-2,4-dione, N-Desmethyl Clobazam, Clofazin, Norclobazam, N-Desmethylclobazam, 1H-1,5-Benzodiazepine-2,4(3H,5H)-dione, 8-chloro-1-phenyl-, Clobazam EP Impurity A, 8-chloro-1-phenyl-1H-benzo[b][1,4]diazepine-2,4(3H,5H)-dione, N-Demethylclobazam, 7-Chloro-5-phenyl-1,5-dihydro-3H-1,5-benzodiazepine-2,4-dione (Norclobazam)

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H317May cause an allergic skin reaction
H336May cause drowsiness or dizziness

Precautionary statements: P261, P271, P272, P280, P302 + P352, P304 + P340, P319, P321, P333 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Clobazam Impurity A?

The CAS Registry Number of Clobazam Impurity A is 22316-55-8. It is also known as Desmethylclobazam, 8-Chloro-1-phenyl-1H-1,5-benzodiazepine-2,4(3H,5H)-dione, 7-Chloro-5-phenyl-1,5-dihydro-3H-1,5-benzodiazepine-2,4-dione.

What is the molecular formula and molecular weight of Clobazam Impurity A?

Clobazam Impurity A has the molecular formula C15H11ClN2O2 and a molecular weight of 286.71 g/mol. Its IUPAC name is 7-chloro-5-phenyl-1H-1,5-benzodiazepine-2,4-dione.

What is Clobazam Impurity A used for?

Clobazam Impurity A is supplied as a characterised reference material related to Clobazam. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Clobazam Impurity A can I order?

We supply Clobazam Impurity A in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Clobazam Impurity A?

Yes. Every lot of Clobazam Impurity A is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Clobazam Impurity A be shipped internationally?

Yes. Clobazam Impurity A is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.