1-(2-(4-(Chloromethyl)phenoxy)ethyl)azepane hydrochloride
Synonyms: 1-(2-(4-(Chloromethyl)phenoxy)ethyl)azepane (HCl Salt) · 1H-Azepine, 1-[2-[4-(chloromethyl)phenoxy]ethyl]hexahydro-, hydrochloride (1:1) · 1H-Azepine, 1-(2-(4-(chloromethyl)phenoxy)ethyl)hexahydro-, hydrochloride (1:1) · 1-[2-[4-(ChloroMethyl)phenoxy]ethyl]hexahydro-1H-azepine hydrochloride
1-(2-(4-(Chloromethyl)phenoxy)ethyl)azepane hydrochloride (CAS 223251-25-0) – Bazedoxifene impurity standard. C15H23Cl2NO, MW 304.3. COA included.
About 1-(2-(4-(Chloromethyl)phenoxy)ethyl)azepane hydrochloride
Listed under CAS 223251-25-0, 1-(2-(4-(Chloromethyl)phenoxy)ethyl)azepane hydrochloride is an impurity of Bazedoxifene available from Vaqora Chemicals. The compound has the formula C15H23Cl2NO, corresponding to a molecular weight of 304.3 g/mol. It is also known as CS-M1883.
It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.
Pharmaceutical QC and development laboratories use this impurity standard of Bazedoxifene to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.
Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.
Typical applications
- Analytical method development
- Method validation (AMV)
- QC release testing
- ANDA / DMF filings
Industries
View every impurity, metabolite and intermediate we list for Bazedoxifene.
Bazedoxifene impuritiesSpecifications & identifiers
| Product name | 1-(2-(4-(Chloromethyl)phenoxy)ethyl)azepane hydrochloride |
|---|---|
| Catalogue No. | VQ-020897 |
| CAS Number | 223251-25-0 |
| IUPAC name | 1-[2-[4-(chloromethyl)phenoxy]ethyl]azepane;hydrochloride |
| Molecular formula | C15H23Cl2NO |
| Molecular weight | 304.3 g/mol |
| Exact mass | 303.1157 |
| Grade | Reference Standard |
| HSN code | 38229090 |
| InChIKey | RMVQWASPAGLTRZ-UHFFFAOYSA-N |
| SMILES | C1CCCN(CC1)CCOC2=CC=C(C=C2)CCl.Cl |
| PubChem CID | 9882909 |
| Physical form | Solid |
|---|---|
| H-bond donors / acceptors | 1 / 2 |
| TPSA | 12.5 Ų |
| Synonyms | 1-(2-(4-(Chloromethyl)phenoxy)ethyl)azepane (HCl Salt), 1H-Azepine, 1-[2-[4-(chloromethyl)phenoxy]ethyl]hexahydro-, hydrochloride (1:1), 1H-Azepine, 1-(2-(4-(chloromethyl)phenoxy)ethyl)hexahydro-, hydrochloride (1:1), 1-[2-[4-(ChloroMethyl)phenoxy]ethyl]hexahydro-1H-azepine hydrochloride, 1-(2-(4-(chloromethyl)phenoxy)ethyl)azepane HCl, CS-M1883, 1-{2-[4-(Chloromethyl)phenoxy]ethyl}azepane--hydrogen chloride (1/1) |
Safety & hazard information (GHS)
Signal word: Danger
Hazard statements
H302Harmful if swallowedH315Causes skin irritationH317May cause an allergic skin reactionH318Causes serious eye damageH319Causes serious eye irritationH335May cause respiratory irritationH412Harmful to aquatic life with long lasting effects
Precautionary statements: P261, P264, P264 + P265, P270, P271, P272, P273, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P305 + P354 + P338, P317, P319, P321, P330, P332 + P317, P333 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501
Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.
Documents
Frequently asked questions
What is the CAS number of 1-(2-(4-(Chloromethyl)phenoxy)ethyl)azepane hydrochloride?
The CAS Registry Number of 1-(2-(4-(Chloromethyl)phenoxy)ethyl)azepane hydrochloride is 223251-25-0. It is also known as 1-(2-(4-(Chloromethyl)phenoxy)ethyl)azepane (HCl Salt), 1H-Azepine, 1-[2-[4-(chloromethyl)phenoxy]ethyl]hexahydro-, hydrochloride (1:1), 1H-Azepine, 1-(2-(4-(chloromethyl)phenoxy)ethyl)hexahydro-, hydrochloride (1:1).
What is the molecular formula and molecular weight of 1-(2-(4-(Chloromethyl)phenoxy)ethyl)azepane hydrochloride?
1-(2-(4-(Chloromethyl)phenoxy)ethyl)azepane hydrochloride has the molecular formula C15H23Cl2NO and a molecular weight of 304.3 g/mol.
What is 1-(2-(4-(Chloromethyl)phenoxy)ethyl)azepane hydrochloride used for?
1-(2-(4-(Chloromethyl)phenoxy)ethyl)azepane hydrochloride is supplied as a characterised reference material related to Bazedoxifene. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.
Which grade and pack sizes of 1-(2-(4-(Chloromethyl)phenoxy)ethyl)azepane hydrochloride can I order?
We supply 1-(2-(4-(Chloromethyl)phenoxy)ethyl)azepane hydrochloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.
Do you provide a COA and SDS with 1-(2-(4-(Chloromethyl)phenoxy)ethyl)azepane hydrochloride?
Yes. Every lot of 1-(2-(4-(Chloromethyl)phenoxy)ethyl)azepane hydrochloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.
Can 1-(2-(4-(Chloromethyl)phenoxy)ethyl)azepane hydrochloride be shipped internationally?
Yes. 1-(2-(4-(Chloromethyl)phenoxy)ethyl)azepane hydrochloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.
Enquire about 1-(2-(4-(Chloromethyl)phenoxy)ethyl)azepane hydrochloride
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