6α-Hydroxy Cortisol

Name: 6α-Hydroxy Cortisol
Brand: Vaqora Chemicals
SKU: VQ-031089

About 6α-Hydroxy Cortisol

6α-Hydroxy Cortisol (CAS 2242-98-0) is a metabolite or degradation product of Hydrocortisone offered by Vaqora Chemicals. Formula C21H30O6, molecular weight 378.5 g/mol. It is also known as 6alpha-Hydroxycortisol or 6|A-Hydroxycortisol.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

Analytical teams use this compound to identify metabolites and degradants of Hydrocortisone, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer 6α-Hydroxy Cortisol in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Hydrocortisone

View every impurity, metabolite and intermediate we list for Hydrocortisone.

Hydrocortisone impurities

Specifications & identifiers

Chemical identifiers
Product name	6α-Hydroxy Cortisol
Catalogue No.	VQ-031089
CAS Number	2242-98-0
IUPAC name	(6S,8S,9S,10R,11S,13S,14S,17R)-6,11,17-trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
Molecular formula	C₂₁H₃₀O₆
Molecular weight	378.5 g/mol
Exact mass	378.2042
Grade	Reference Standard
HSN code	38229090
InChIKey	GNFTWPCIRXSCQF-HVIRSNARSA-N
SMILES	C[C@]12CCC(=O)C=C1[C@H](C[C@@H]3[C@@H]2[C@H](C[C@]4([C@H]3CC[C@@]4(C(=O)CO)O)C)O)O
PubChem CID	254633

Physical properties
Physical form	Solid
LogP (XLogP3)	0.3
H-bond donors / acceptors	4 / 6
TPSA	115 Å²
Synonyms	6alpha-Hydroxycortisol, 6alpha,11beta,17,21-Tetrahydroxypregn-4-ene-3,20-dione, 6, A-Hydroxycortisol, 6a-Hydroxy Cortisol, 6alpha-Hydroxy Cortisol, 6I+/--Hydroxycortisol, 6alpha-Hydroxyhydrocortisone, 6a,17-Dihydroxy-corticosterone, 6a,11b,17,21-Tetrahydroxy-pregn-4-ene-3,20-dione

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H341Suspected of causing genetic defects

Precautionary statements: P203, P264, P270, P280, P301 + P317, P318, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 6α-Hydroxy Cortisol?

The CAS Registry Number of 6α-Hydroxy Cortisol is 2242-98-0. It is also known as 6alpha-Hydroxycortisol, 6alpha,11beta,17,21-Tetrahydroxypregn-4-ene-3,20-dione, 6.

What is the molecular formula and molecular weight of 6α-Hydroxy Cortisol?

6α-Hydroxy Cortisol has the molecular formula C21H30O6 and a molecular weight of 378.5 g/mol. Its IUPAC name is (6S,8S,9S,10R,11S,13S,14S,17R)-6,11,17-trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one.

What is 6α-Hydroxy Cortisol used for?

6α-Hydroxy Cortisol is supplied as a characterised reference material related to Hydrocortisone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 6α-Hydroxy Cortisol can I order?

We supply 6α-Hydroxy Cortisol in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 6α-Hydroxy Cortisol?

Yes. Every lot of 6α-Hydroxy Cortisol is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 6α-Hydroxy Cortisol be shipped internationally?

Yes. 6α-Hydroxy Cortisol is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.