N-Demethylclindamycin

Name: N-Demethylclindamycin
Brand: Vaqora Chemicals
SKU: VQ-029850

About N-Demethylclindamycin

N-Demethylclindamycin (CAS 22431-45-4) is a metabolite or degradation product of Clindamycin offered by Vaqora Chemicals. Formula C17H31ClN2O5S, molecular weight 411.0 g/mol. Alternative names: 7-Chloro-N-demethyllincomycin and (7S)-7-Chloro-7-deoxy-1'-demethyllincomycin.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Analytical teams use this compound to identify metabolites and degradants of Clindamycin, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Clindamycin

View every impurity, metabolite and intermediate we list for Clindamycin.

Clindamycin impurities

Specifications & identifiers

Chemical identifiers
Product name	N-Demethylclindamycin
Catalogue No.	VQ-029850
CAS Number	22431-45-4
IUPAC name	(2S,4R)-N-[(1S,2S)-2-chloro-1-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-methylsulfanyloxan-2-yl]propyl]-4-propylpyrrolidine-2-carboxamide
Molecular formula	C₁₇H₃₁ClN₂O₅S
Molecular weight	411 g/mol
Exact mass	410.1642
Grade	Reference Standard
HSN code	38229090
InChIKey	HDBHHHCDEYATPY-MHXMMLMNSA-N
SMILES	CCC[C@@H]1C[C@H](NC1)C(=O)N[C@@H]([C@@H]2[C@@H]([C@@H]([C@H]([C@H](O2)SC)O)O)O)[C@H](C)Cl
PubChem CID	101276943

Physical properties
Physical form	Solid
LogP (XLogP3)	1.7
H-bond donors / acceptors	5 / 7
TPSA	136 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Demethylclindamycin?

The CAS Registry Number of N-Demethylclindamycin is 22431-45-4. It is also known as 7-Chloro-N-demethyllincomycin, (7S)-7-Chloro-7-deoxy-1'-demethyllincomycin.

What is the molecular formula and molecular weight of N-Demethylclindamycin?

N-Demethylclindamycin has the molecular formula C17H31ClN2O5S and a molecular weight of 411 g/mol. Its IUPAC name is (2S,4R)-N-[(1S,2S)-2-chloro-1-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-methylsulfanyloxan-2-yl]propyl]-4-propylpyrrolidine-2-carboxamide.

What is N-Demethylclindamycin used for?

N-Demethylclindamycin is supplied as a characterised reference material related to Clindamycin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-Demethylclindamycin can I order?

We supply N-Demethylclindamycin in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Demethylclindamycin?

Yes. Every lot of N-Demethylclindamycin is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Demethylclindamycin be shipped internationally?

Yes. We export N-Demethylclindamycin worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.