Niraparib Methyl Ester Impurity

About Niraparib Methyl Ester Impurity

Niraparib Methyl Ester Impurity is an impurity of Niraparib carrying the CAS registry number 2244220-34-4. Formula C20H21N3O2, molecular weight 335.4 g/mol. Systematically, it is named methyl 2-[4-[(3S)-piperidin-3-yl]phenyl]indazole-7-carboxylate. Alternative names: Niraparib Impurity 76 and Niraparib Impurity 5.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Pharmaceutical QC and development laboratories use this impurity standard of Niraparib to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Niraparib Methyl Ester Impurity is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Niraparib

View every impurity, metabolite and intermediate we list for Niraparib.

Niraparib impurities

Specifications & identifiers

Chemical identifiers
Product name	Niraparib Methyl Ester Impurity
Catalogue No.	VQ-005390
CAS Number	2244220-34-4
IUPAC name	methyl 2-[4-[(3S)-piperidin-3-yl]phenyl]indazole-7-carboxylate
Molecular formula	C₂₀H₂₁N₃O₂
Molecular weight	335.4 g/mol
Exact mass	335.1634
Grade	Reference Standard
HSN code	38229090
InChIKey	KVOTYRJIHODCAI-OAHLLOKOSA-N
SMILES	COC(=O)C1=CC=CC2=CN(N=C21)C3=CC=C(C=C3)[C@@H]4CCCNC4
PubChem CID	141482258

Physical properties
Physical form	Solid
LogP (XLogP3)	3.2
H-bond donors / acceptors	1 / 4
TPSA	56.2 Å²
Synonyms	Methyl 2-[4-(3S)-3-piperidinylphenyl]-2H-indazole-7-carboxylate, (S)-Methyl 2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-carboxylate, Methyl (S)-2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-carboxylate, Niraparib Impurity 76, 2H-Indazole-7-carboxylic acid, 2-(4-(3S)-3-piperidinylphenyl)-, methyl ester, Niraparib Impurity 5

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Niraparib Methyl Ester Impurity?

The CAS Registry Number of Niraparib Methyl Ester Impurity is 2244220-34-4. It is also known as Methyl 2-[4-(3S)-3-piperidinylphenyl]-2H-indazole-7-carboxylate, (S)-Methyl 2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-carboxylate, Methyl (S)-2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-carboxylate.

What is the molecular formula and molecular weight of Niraparib Methyl Ester Impurity?

Niraparib Methyl Ester Impurity has the molecular formula C20H21N3O2 and a molecular weight of 335.4 g/mol. Its IUPAC name is methyl 2-[4-[(3S)-piperidin-3-yl]phenyl]indazole-7-carboxylate.

What is Niraparib Methyl Ester Impurity used for?

Niraparib Methyl Ester Impurity is supplied as a characterised reference material related to Niraparib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Niraparib Methyl Ester Impurity can I order?

We supply Niraparib Methyl Ester Impurity in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Niraparib Methyl Ester Impurity?

Yes. Every lot of Niraparib Methyl Ester Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Niraparib Methyl Ester Impurity be shipped internationally?

Yes. We export Niraparib Methyl Ester Impurity worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.