Baclofen Impurity A

Name: Baclofen Impurity A
Brand: Vaqora Chemicals
SKU: VQ-004471

About Baclofen Impurity A

Vaqora Chemicals supplies Baclofen Impurity A, an impurity of Baclofen registered under CAS number 22518-27-0, specified at 94.27% purity. With the molecular formula C10H10ClNO, it has a molar mass of 195.64 g/mol. Systematically, it is named 4-(4-chlorophenyl)pyrrolidin-2-one. Alternative names: 4-(p-chlorophenyl)-2-oxopyrrolidine and (±)-Baclofen Lactam.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Danger” with 9 hazard statements. Review the Safety Data Sheet before use.

As a characterised impurity of Baclofen, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 5 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. Stock is available for quick dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Baclofen

View every impurity, metabolite and intermediate we list for Baclofen.

Baclofen impurities

Specifications & identifiers

Chemical identifiers
Product name	Baclofen Impurity A
Catalogue No.	VQ-004471
CAS Number	22518-27-0
Other CAS	113933-06-5
IUPAC name	4-(4-chlorophenyl)pyrrolidin-2-one
Molecular formula	C₁₀H₁₀ClNO
Molecular weight	195.64 g/mol
Exact mass	195.0451
Grade	Reference Standard
Purity / assay	94.27%
HSN code	38229090
InChIKey	OVRPDYOZYMCTAK-UHFFFAOYSA-N
SMILES	C1C(CNC1=O)C2=CC=C(C=C2)Cl
PubChem CID	185490

Physical properties
Physical form	Solid
LogP (XLogP3)	1.6
H-bond donors / acceptors	1 / 1
TPSA	29.1 Å²
Synonyms	4-(p-chlorophenyl)-2-oxopyrrolidine, (±)-Baclofen Lactam, 4-(4-Chlorophenyl)-2-pyrrolidinone, (4RS)-4-(4-Chlorophenyl)pyrrolidin-2-one, (RS)-4-Amino-3-(4-chlorophenyl)butyric Acid Lactam, 4-(4-Chlorophenyl)-2-pyrrolidone, USP Baclofen Related Compound A, Baclofen EP Impurity A, 2-Pyrrolidinone, 4-(4-chlorophenyl)-, 4-(4-Chloro-phenyl)-pyrrolidin-2-one, Baclofen impurity A CRS, (4RS)-4-(4-Chlorophenyl)pyrrolidin-2-one (Baclofen Lactam)

Safety & hazard information (GHS)

Toxic

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H311Toxic in contact with skin
H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H330Fatal if inhaled
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335May cause respiratory irritation
H361Suspected of damaging fertility or the unborn child

Precautionary statements: P203, P233, P260, P261, P262, P264, P264 + P265, P270, P271, P272, P280, P284, P301 + P316, P302 + P352, P304 + P340, P305 + P351 + P338, P316, P318, P319, P320, P321, P330, P332 + P317, P333 + P317

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Baclofen Impurity A?

The CAS Registry Number of Baclofen Impurity A is 22518-27-0. It is also known as 4-(p-chlorophenyl)-2-oxopyrrolidine, (±)-Baclofen Lactam, 4-(4-Chlorophenyl)-2-pyrrolidinone.

What is the molecular formula and molecular weight of Baclofen Impurity A?

Baclofen Impurity A has the molecular formula C10H10ClNO and a molecular weight of 195.64 g/mol. Its IUPAC name is 4-(4-chlorophenyl)pyrrolidin-2-one.

What is Baclofen Impurity A used for?

Baclofen Impurity A is supplied as a characterised reference material related to Baclofen. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Baclofen Impurity A can I order?

We supply Baclofen Impurity A in Reference Standard (94.27%) grade, in 5 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Baclofen Impurity A?

Yes. Every lot of Baclofen Impurity A is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Baclofen Impurity A be shipped internationally?

Yes. Baclofen Impurity A is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.