(S)-7-(But-2-yn-1-yl)-3-Methyl-1-((4-methylqu… 2253964-85-9

Name: (S)-7-(But-2-yn-1-yl)-3-Methyl-1-((4-methylquinazolin-2-yl)methyl)-8-(piperidin-3-ylamino)-3,7-dihydro-1H-purine-2,6-dione
Brand: Vaqora Chemicals
SKU: VQ-026475

About (S)-7-(But-2-yn-1-yl)-3-Methyl-1-((4-methylquinazolin-2-yl)methyl)-8-(piperidin-3-ylamino)-3,7-dihydro-1H-purine-2,6-dione

Listed under CAS 2253964-85-9, (S)-7-(But-2-yn-1-yl)-3-Methyl-1-((4-methylquinazolin-2-yl)methyl)-8-(piperidin-3-ylamino)-3,7-dihydro-1H-purine-2,6-dione is an impurity of Linagliptin available from Vaqora Chemicals. Its molecular formula is C25H28N8O2 and its molecular weight is 472.5 g/mol. The IUPAC name is 7-but-2-ynyl-3-methyl-1-[(4-methylquinazolin-2-yl)methyl]-8-[[(3S)-piperidin-3-yl]amino]purine-2,6-dione.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Linagliptin to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer (S)-7-(But-2-yn-1-yl)-3-Methyl-1-((4-methylquinazolin-2-yl)methyl)-8-(piperidin-3-ylamino)-3,7-dihydro-1H-purine-2,6-dione in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Linagliptin

View every impurity, metabolite and intermediate we list for Linagliptin.

Linagliptin impurities

Specifications & identifiers

Chemical identifiers
Product name	(S)-7-(But-2-yn-1-yl)-3-Methyl-1-((4-methylquinazolin-2-yl)methyl)-8-(piperidin-3-ylamino)-3,7-dihydro-1H-purine-2,6-dione
Catalogue No.	VQ-026475
CAS Number	2253964-85-9
IUPAC name	7-but-2-ynyl-3-methyl-1-[(4-methylquinazolin-2-yl)methyl]-8-[[(3S)-piperidin-3-yl]amino]purine-2,6-dione
Molecular formula	C₂₅H₂₈N₈O₂
Molecular weight	472.5 g/mol
Exact mass	472.2335
Grade	Reference Standard
HSN code	38229090
InChIKey	DOQKYHYFAIBWOA-KRWDZBQOSA-N
SMILES	CC#CCN1C2=C(N=C1N[C@H]3CCCNC3)N(C(=O)N(C2=O)CC4=NC5=CC=CC=C5C(=N4)C)C
PubChem CID	156619826

Physical properties
Physical form	Solid
LogP (XLogP3)	2.3
H-bond donors / acceptors	2 / 7
TPSA	108 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (S)-7-(But-2-yn-1-yl)-3-Methyl-1-((4-methylquinazolin-2-yl)methyl)-8-(piperidin-3-ylamino)-3,7-dihydro-1H-purine-2,6-dione?

The CAS Registry Number of (S)-7-(But-2-yn-1-yl)-3-Methyl-1-((4-methylquinazolin-2-yl)methyl)-8-(piperidin-3-ylamino)-3,7-dihydro-1H-purine-2,6-dione is 2253964-85-9.

What is the molecular formula and molecular weight of (S)-7-(But-2-yn-1-yl)-3-Methyl-1-((4-methylquinazolin-2-yl)methyl)-8-(piperidin-3-ylamino)-3,7-dihydro-1H-purine-2,6-dione?

(S)-7-(But-2-yn-1-yl)-3-Methyl-1-((4-methylquinazolin-2-yl)methyl)-8-(piperidin-3-ylamino)-3,7-dihydro-1H-purine-2,6-dione has the molecular formula C25H28N8O2 and a molecular weight of 472.5 g/mol. Its IUPAC name is 7-but-2-ynyl-3-methyl-1-[(4-methylquinazolin-2-yl)methyl]-8-[[(3S)-piperidin-3-yl]amino]purine-2,6-dione.

What is (S)-7-(But-2-yn-1-yl)-3-Methyl-1-((4-methylquinazolin-2-yl)methyl)-8-(piperidin-3-ylamino)-3,7-dihydro-1H-purine-2,6-dione used for?

(S)-7-(But-2-yn-1-yl)-3-Methyl-1-((4-methylquinazolin-2-yl)methyl)-8-(piperidin-3-ylamino)-3,7-dihydro-1H-purine-2,6-dione is supplied as a characterised reference material related to Linagliptin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (S)-7-(But-2-yn-1-yl)-3-Methyl-1-((4-methylquinazolin-2-yl)methyl)-8-(piperidin-3-ylamino)-3,7-dihydro-1H-purine-2,6-dione can I order?

We supply (S)-7-(But-2-yn-1-yl)-3-Methyl-1-((4-methylquinazolin-2-yl)methyl)-8-(piperidin-3-ylamino)-3,7-dihydro-1H-purine-2,6-dione in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (S)-7-(But-2-yn-1-yl)-3-Methyl-1-((4-methylquinazolin-2-yl)methyl)-8-(piperidin-3-ylamino)-3,7-dihydro-1H-purine-2,6-dione?

Yes. Every lot of (S)-7-(But-2-yn-1-yl)-3-Methyl-1-((4-methylquinazolin-2-yl)methyl)-8-(piperidin-3-ylamino)-3,7-dihydro-1H-purine-2,6-dione is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (S)-7-(But-2-yn-1-yl)-3-Methyl-1-((4-methylquinazolin-2-yl)methyl)-8-(piperidin-3-ylamino)-3,7-dihydro-1H-purine-2,6-dione be shipped internationally?

Yes. We export (S)-7-(But-2-yn-1-yl)-3-Methyl-1-((4-methylquinazolin-2-yl)methyl)-8-(piperidin-3-ylamino)-3,7-dihydro-1H-purine-2,6-dione worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.