VNL7-VNL5 (Venetoclax Dimer Impurity 2)

About VNL7-VNL5 (Venetoclax Dimer Impurity 2)

VNL7-VNL5 (Venetoclax Dimer Impurity 2) is an impurity of Venetoclax carrying the CAS registry number 2270190-88-8, specified at 34% purity. Formula C78H83Cl2N11O9S, molecular weight 1421.5 g/mol. Common synonyms include Venetoclax Impurity S2B.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

As a characterised impurity of Venetoclax, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer VNL7-VNL5 (Venetoclax Dimer Impurity 2) in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. Stock is available for quick dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Venetoclax

View every impurity, metabolite and intermediate we list for Venetoclax.

Venetoclax impurities

Specifications & identifiers

Chemical identifiers
Product name	VNL7-VNL5 (Venetoclax Dimer Impurity 2)
Catalogue No.	VQ-006174
CAS Number	2270190-88-8
IUPAC name	4-[4-[[2-(4-chlorophenyl)-4,4-dimethylcyclohexen-1-yl]methyl]piperazin-1-yl]-2-[1-[4-[4-[[2-(4-chlorophenyl)-4,4-dimethylcyclohexen-1-yl]methyl]piperazin-1-yl]-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)benzoyl]pyrrolo[2,3-b]pyridin-5-yl]oxy-N-[3-nitro-4-(oxan-4-ylmethylamino)phenyl]sulfonylbenzamide
Molecular formula	C₇₈H₈₃Cl₂N₁₁O₉S
Molecular weight	1421.5 g/mol
Exact mass	1419.5473
Grade	Reference Standard
Purity / assay	34%
HSN code	38229090
InChIKey	KZRJVBYNDFMXPA-UHFFFAOYSA-N
SMILES	CC1(CCC(=C(C1)C2=CC=C(C=C2)Cl)CN3CCN(CC3)C4=CC(=C(C=C4)C(=O)NS(=O)(=O)C5=CC(=C(C=C5)NCC6CCOCC6)[N+](=O)[O-])OC7=CN=C8C(=C7)C=CN8C(=O)C9=C(C=C(C=C9)N1CCN(CC1)CC1=C(CC(CC1)(C)C)C1=CC=C(C=C1)Cl)OC1=CN=C2C(=C1)C=CN2)C
PubChem CID	169447704

Physical properties
Physical form	Solid
LogP (XLogP3)	14.6
H-bond donors / acceptors	3 / 16
TPSA	234 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of VNL7-VNL5 (Venetoclax Dimer Impurity 2)?

The CAS Registry Number of VNL7-VNL5 (Venetoclax Dimer Impurity 2) is 2270190-88-8. It is also known as Venetoclax Impurity S2B.

What is the molecular formula and molecular weight of VNL7-VNL5 (Venetoclax Dimer Impurity 2)?

VNL7-VNL5 (Venetoclax Dimer Impurity 2) has the molecular formula C78H83Cl2N11O9S and a molecular weight of 1421.5 g/mol.

What is VNL7-VNL5 (Venetoclax Dimer Impurity 2) used for?

VNL7-VNL5 (Venetoclax Dimer Impurity 2) is supplied as a characterised reference material related to Venetoclax. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of VNL7-VNL5 (Venetoclax Dimer Impurity 2) can I order?

We supply VNL7-VNL5 (Venetoclax Dimer Impurity 2) in Reference Standard (34%) grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with VNL7-VNL5 (Venetoclax Dimer Impurity 2)?

Yes. Every lot of VNL7-VNL5 (Venetoclax Dimer Impurity 2) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can VNL7-VNL5 (Venetoclax Dimer Impurity 2) be shipped internationally?

Yes. We export VNL7-VNL5 (Venetoclax Dimer Impurity 2) worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.