Famprofazone

About Famprofazone

Famprofazone is a high-purity reference standard of Fomepizole carrying the CAS registry number 22881-35-2. With the molecular formula C24H31N3O, it has a molar mass of 377.5 g/mol. Its systematic (IUPAC) name is 1-methyl-5-[[methyl(1-phenylpropan-2-yl)amino]methyl]-2-phenyl-4-propan-2-ylpyrazol-3-one. Common synonyms include Geodowin.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Warning” with 1 hazard statement. Review the Safety Data Sheet before use.

As a reference sample of Fomepizole, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Famprofazone is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Fomepizole

View every impurity, metabolite and intermediate we list for Fomepizole.

Fomepizole impurities

Specifications & identifiers

Chemical identifiers
Product name	Famprofazone
Catalogue No.	VQ-048458
CAS Number	22881-35-2
IUPAC name	1-methyl-5-[[methyl(1-phenylpropan-2-yl)amino]methyl]-2-phenyl-4-propan-2-ylpyrazol-3-one
Molecular formula	C₂₄H₃₁N₃O
Molecular weight	377.5 g/mol
Exact mass	377.2467
Grade	Reference Standard
HSN code	38229090
InChIKey	GNUXVOXXWGNPIV-UHFFFAOYSA-N
SMILES	CC(C)C1=C(N(N(C1=O)C2=CC=CC=C2)C)CN(C)C(C)CC3=CC=CC=C3
PubChem CID	3326

Physical properties
Physical form	Solid
LogP (XLogP3)	5
H-bond donors / acceptors	0 / 3
TPSA	26.8 Å²
Synonyms	Pyrazolin-5-one, 4-isopropyl-2-methyl-1-phenyl-3-((1-phenyl-2-propyl)methylamino)methyl-, Geodowin, Antipyrine, 4-isopropyl-3-(alpha-(methyl-(1-phenyl-2-propyl)amino))-, 3-(N-Methyl-(alpha-methyl-beta-phenyl)-ethyl-aminomethyl)-4-isopropyl-norantipyrine, Antipyrine, 4-isopropyl-3-(.alpha.-(methyl-(1-phenyl-2-propyl)amino))-, 3-(N,.alpha.-Dimethylphenethylaminomethyl)-4-isopropyl-2-methyl-1-phenyl-3-pyrazolin-5-one, 3-(N-Methyl-(.alpha.-methyl-.beta.-phenyl)-ethyl-aminomethyl)-4-isopropyl-norantipyrine

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Famprofazone?

The CAS Registry Number of Famprofazone is 22881-35-2. It is also known as Pyrazolin-5-one, 4-isopropyl-2-methyl-1-phenyl-3-((1-phenyl-2-propyl)methylamino)methyl-, Geodowin, Antipyrine, 4-isopropyl-3-(alpha-(methyl-(1-phenyl-2-propyl)amino))-.

What is the molecular formula and molecular weight of Famprofazone?

Famprofazone has the molecular formula C24H31N3O and a molecular weight of 377.5 g/mol. Its IUPAC name is 1-methyl-5-[[methyl(1-phenylpropan-2-yl)amino]methyl]-2-phenyl-4-propan-2-ylpyrazol-3-one.

What is Famprofazone used for?

Famprofazone is supplied as a characterised reference material related to Fomepizole. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Famprofazone can I order?

We supply Famprofazone in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Famprofazone?

Yes. Every lot of Famprofazone is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Famprofazone be shipped internationally?

Yes. Famprofazone is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.