1,4-Bis((6-chloropyridin-3-yl)methyl)piperazi… 230617-68-2

Name: 1,4-Bis((6-chloropyridin-3-yl)methyl)piperazine
Brand: Vaqora Chemicals
SKU: VQ-045081

About 1,4-Bis((6-chloropyridin-3-yl)methyl)piperazine

Listed under CAS 230617-68-2, 1,4-Bis((6-chloropyridin-3-yl)methyl)piperazine is an impurity of Abemaciclib available from Vaqora Chemicals. Its molecular formula is C16H18Cl2N4 and its molecular weight is 337.2 g/mol. The IUPAC name is 1,4-bis[(6-chloro-3-pyridinyl)methyl]piperazine.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Pharmaceutical QC and development laboratories use this impurity standard of Abemaciclib to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 1,4-Bis((6-chloropyridin-3-yl)methyl)piperazine in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Abemaciclib

View every impurity, metabolite and intermediate we list for Abemaciclib.

Abemaciclib impurities

Specifications & identifiers

Chemical identifiers
Product name	1,4-Bis((6-chloropyridin-3-yl)methyl)piperazine
Catalogue No.	VQ-045081
CAS Number	230617-68-2
IUPAC name	1,4-bis[(6-chloro-3-pyridinyl)methyl]piperazine
Molecular formula	C₁₆H₁₈Cl₂N₄
Molecular weight	337.2 g/mol
Exact mass	336.0909
Grade	Reference Standard
HSN code	38229090
InChIKey	CNGZCJSVMLVNQC-UHFFFAOYSA-N
SMILES	C1CN(CCN1CC2=CN=C(C=C2)Cl)CC3=CN=C(C=C3)Cl
PubChem CID	10759360

Physical properties
Physical form	Solid
LogP (XLogP3)	2.8
H-bond donors / acceptors	0 / 4
TPSA	32.3 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 1,4-Bis((6-chloropyridin-3-yl)methyl)piperazine?

The CAS Registry Number of 1,4-Bis((6-chloropyridin-3-yl)methyl)piperazine is 230617-68-2. It is also known as Piperazine, 1,4-bis[(6-chloro-3-pyridinyl)methyl]-.

What is the molecular formula and molecular weight of 1,4-Bis((6-chloropyridin-3-yl)methyl)piperazine?

1,4-Bis((6-chloropyridin-3-yl)methyl)piperazine has the molecular formula C16H18Cl2N4 and a molecular weight of 337.2 g/mol. Its IUPAC name is 1,4-bis[(6-chloro-3-pyridinyl)methyl]piperazine.

What is 1,4-Bis((6-chloropyridin-3-yl)methyl)piperazine used for?

1,4-Bis((6-chloropyridin-3-yl)methyl)piperazine is supplied as a characterised reference material related to Abemaciclib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 1,4-Bis((6-chloropyridin-3-yl)methyl)piperazine can I order?

We supply 1,4-Bis((6-chloropyridin-3-yl)methyl)piperazine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 1,4-Bis((6-chloropyridin-3-yl)methyl)piperazine?

Yes. Every lot of 1,4-Bis((6-chloropyridin-3-yl)methyl)piperazine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 1,4-Bis((6-chloropyridin-3-yl)methyl)piperazine be shipped internationally?

Yes. We export 1,4-Bis((6-chloropyridin-3-yl)methyl)piperazine worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.