Probucol

About Probucol

Probucol is a high-purity reference standard of Probucol carrying the CAS registry number 23288-49-5. Its molecular formula is C31H48O2S2 and its molecular weight is 516.8 g/mol. Its systematic (IUPAC) name is 2,6-ditert-butyl-4-[2-(3,5-ditert-butyl-4-hydroxyphenyl)sulfanylpropan-2-ylsulfanyl]phenol. Alternative names: DH-581 and Sinlestal.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

As a reference sample of Probucol, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer Probucol in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Probucol

View every impurity, metabolite and intermediate we list for Probucol.

Probucol impurities

Specifications & identifiers

Chemical identifiers
Product name	Probucol
Catalogue No.	VQ-041671
CAS Number	23288-49-5
IUPAC name	2,6-ditert-butyl-4-[2-(3,5-ditert-butyl-4-hydroxyphenyl)sulfanylpropan-2-ylsulfanyl]phenol
Molecular formula	C₃₁H₄₈O₂S₂
Molecular weight	516.8 g/mol
Exact mass	516.3096
Grade	Reference Standard
HSN code	38229090
InChIKey	FYPMFJGVHOHGLL-UHFFFAOYSA-N
SMILES	CC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)SC(C)(C)SC2=CC(=C(C(=C2)C(C)(C)C)O)C(C)(C)C
PubChem CID	4912

Physical properties
Physical form	Solid
LogP (XLogP3)	11.3
H-bond donors / acceptors	2 / 4
TPSA	91.1 Å²
Synonyms	DH-581, Sinlestal, DH 581, Acetone bis(3,5-di-tert-butyl-4-hydroxyphenyl) mercaptole, 4,4'-(Isopropylidenedithio)bis(2,6-di-tert-butylphenol), 4,4'-(Isopropylidenedithio)bis[2,6-di-tert-butylphenol], 2,6-ditert-butyl-4-(2-(3,5-ditert-butyl-4-hydroxyphenyl)sulfanylpropan-2-ylsulfanyl)phenol, 4,4'-(Propan-2,2-diylbis(sulfandiyl))bis(2,6-bis(1,1-dimethylethyl)phenol), Phenol, 4,4'-((1-methylethylidene)bis(thio))bis(2,6-bis(1,1-dimethylethyl))-, Lesterol

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Probucol?

The CAS Registry Number of Probucol is 23288-49-5. It is also known as DH-581, Sinlestal, DH 581.

What is the molecular formula and molecular weight of Probucol?

Probucol has the molecular formula C31H48O2S2 and a molecular weight of 516.8 g/mol. Its IUPAC name is 2,6-ditert-butyl-4-[2-(3,5-ditert-butyl-4-hydroxyphenyl)sulfanylpropan-2-ylsulfanyl]phenol.

What is Probucol used for?

Probucol is supplied as a characterised reference material related to Probucol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Probucol can I order?

We supply Probucol in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Probucol?

Yes. Every lot of Probucol is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Probucol be shipped internationally?

Yes. Probucol is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.