DL-threo-Methylphenidate hydrochloride

About DL-threo-Methylphenidate hydrochloride

DL-threo-Methylphenidate hydrochloride is an impurity of Methylphenidate carrying the CAS registry number 23655-65-4. Its molecular formula is C14H20ClNO2 and its molecular weight is 269.77 g/mol. Alternative names: Dexmethylphenidate hydrochloride and Focalin.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

As a characterised impurity of Methylphenidate, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer DL-threo-Methylphenidate hydrochloride in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Methylphenidate

View every impurity, metabolite and intermediate we list for Methylphenidate.

Methylphenidate impurities

Specifications & identifiers

Chemical identifiers
Product name	DL-threo-Methylphenidate hydrochloride
Catalogue No.	VQ-044899
CAS Number	23655-65-4
IUPAC name	methyl (2R)-2-phenyl-2-[(2R)-piperidin-2-yl]acetate;hydrochloride
Molecular formula	C₁₄H₂₀ClNO₂
Molecular weight	269.77 g/mol
Exact mass	269.1183
Grade	Reference Standard
HSN code	38229090
InChIKey	JUMYIBMBTDDLNG-OJERSXHUSA-N
SMILES	COC(=O)[C@@H]([C@H]1CCCCN1)C2=CC=CC=C2.Cl
PubChem CID	154100

Physical properties
Physical form	Solid
H-bond donors / acceptors	2 / 3
TPSA	38.3 Å²
Synonyms	Dexmethylphenidate hydrochloride, Focalin, D-threo-Methylphenidate hydrochloride, dex-methylphenidate hydrochloride, Methylphenidate d-threo-form hydrochloride, 2-Piperidineacetic acid, alpha-phenyl-, methyl ester, hydrochloride, (alphaR,2R)-, XR, Focalin, Hydrochloride, Dexmethylphenidate, Dexmethylphenidate Hydrochloride Extended-release, Dexmethylphenidate HCl, Focalin XR, rac-threo-Methylphenidate Hydrochloride

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of DL-threo-Methylphenidate hydrochloride?

The CAS Registry Number of DL-threo-Methylphenidate hydrochloride is 23655-65-4. It is also known as Dexmethylphenidate hydrochloride, Focalin, D-threo-Methylphenidate hydrochloride.

What is the molecular formula and molecular weight of DL-threo-Methylphenidate hydrochloride?

DL-threo-Methylphenidate hydrochloride has the molecular formula C14H20ClNO2 and a molecular weight of 269.77 g/mol.

What is DL-threo-Methylphenidate hydrochloride used for?

DL-threo-Methylphenidate hydrochloride is supplied as a characterised reference material related to Methylphenidate. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of DL-threo-Methylphenidate hydrochloride can I order?

We supply DL-threo-Methylphenidate hydrochloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with DL-threo-Methylphenidate hydrochloride?

Yes. Every lot of DL-threo-Methylphenidate hydrochloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can DL-threo-Methylphenidate hydrochloride be shipped internationally?

Yes. DL-threo-Methylphenidate hydrochloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.