6-Aminoisoquinoline

About 6-Aminoisoquinoline

6-Aminoisoquinoline is an impurity of Netarsudil carrying the CAS registry number 23687-26-5. Its molecular formula is C9H8N2 and its molecular weight is 144.17 g/mol. The IUPAC name is isoquinolin-6-amine. Common synonyms include 6-Isoquinolinamine and Isoquinoline, 6-amino-.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 4 hazard statements. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Netarsudil to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer 6-Aminoisoquinoline in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Netarsudil

View every impurity, metabolite and intermediate we list for Netarsudil.

Netarsudil impurities

Specifications & identifiers

Chemical identifiers
Product name	6-Aminoisoquinoline
Catalogue No.	VQ-023379
CAS Number	23687-26-5
IUPAC name	isoquinolin-6-amine
Molecular formula	C₉H₈N₂
Molecular weight	144.17 g/mol
Exact mass	144.0687
Grade	Reference Standard
HSN code	38229090
InChIKey	NGFCTYXFMDWFRQ-UHFFFAOYSA-N
SMILES	C1=CC2=C(C=CN=C2)C=C1N
PubChem CID	588991

Physical properties
Physical form	Solid
LogP (XLogP3)	1.6
H-bond donors / acceptors	1 / 2
TPSA	38.9 Å²

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 6-Aminoisoquinoline?

The CAS Registry Number of 6-Aminoisoquinoline is 23687-26-5. It is also known as 6-Isoquinolinamine, Isoquinoline, 6-amino-, Isoquinolin-6-ylamine.

What is the molecular formula and molecular weight of 6-Aminoisoquinoline?

6-Aminoisoquinoline has the molecular formula C9H8N2 and a molecular weight of 144.17 g/mol. Its IUPAC name is isoquinolin-6-amine.

What is 6-Aminoisoquinoline used for?

6-Aminoisoquinoline is supplied as a characterised reference material related to Netarsudil. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 6-Aminoisoquinoline can I order?

We supply 6-Aminoisoquinoline in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 6-Aminoisoquinoline?

Yes. Every lot of 6-Aminoisoquinoline is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 6-Aminoisoquinoline be shipped internationally?

Yes. 6-Aminoisoquinoline is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.