2,2,2-Crypt

About 2,2,2-Crypt

2,2,2-Crypt is an impurity of Fludeoxyglucose carrying the CAS registry number 23978-09-8. Formula C18H36N2O6, molecular weight 376.5 g/mol. Its systematic (IUPAC) name is 4,7,13,16,21,24-hexaoxa-1,10-diazabicyclo[8.8.8]hexacosane. Alternative names: Cryptand 222 and Cryptating agent 222.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Fludeoxyglucose to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 2,2,2-Crypt is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Fludeoxyglucose

View every impurity, metabolite and intermediate we list for Fludeoxyglucose.

Fludeoxyglucose impurities

Specifications & identifiers

Chemical identifiers
Product name	2,2,2-Crypt
Catalogue No.	VQ-043544
CAS Number	23978-09-8
IUPAC name	4,7,13,16,21,24-hexaoxa-1,10-diazabicyclo[8.8.8]hexacosane
Molecular formula	C₁₈H₃₆N₂O₆
Molecular weight	376.5 g/mol
Exact mass	376.2573
Grade	Reference Standard
HSN code	38229090
InChIKey	AUFVJZSDSXXFOI-UHFFFAOYSA-N
SMILES	C1COCCOCCN2CCOCCOCCN1CCOCCOCC2
PubChem CID	72801

Physical properties
Physical form	Solid
LogP (XLogP3)	-1
H-bond donors / acceptors	0 / 8
TPSA	61.9 Å²
Synonyms	Cryptand 222, Cryptating agent 222, Cryptate 222, Ligand 222, Cryptofix 222, Kriptofix 222, Kryptand 222, Cryptand C 222, 2,2,2-Cryptand, Cryptand-222, 4,7,13,16,21,24-Hexaoxa-1,10-diazabicyclo(8.8.8)hexacosane

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2,2,2-Crypt?

The CAS Registry Number of 2,2,2-Crypt is 23978-09-8. It is also known as Cryptand 222, Cryptating agent 222, Cryptate 222.

What is the molecular formula and molecular weight of 2,2,2-Crypt?

2,2,2-Crypt has the molecular formula C18H36N2O6 and a molecular weight of 376.5 g/mol. Its IUPAC name is 4,7,13,16,21,24-hexaoxa-1,10-diazabicyclo[8.8.8]hexacosane.

What is 2,2,2-Crypt used for?

2,2,2-Crypt is supplied as a characterised reference material related to Fludeoxyglucose. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2,2,2-Crypt can I order?

We supply 2,2,2-Crypt in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2,2,2-Crypt?

Yes. Every lot of 2,2,2-Crypt is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2,2,2-Crypt be shipped internationally?

Yes. 2,2,2-Crypt is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.