4-Hydroxy-5-methoxy-2-nitrobenzaldehyde

Name: 4-Hydroxy-5-methoxy-2-nitrobenzaldehyde
Brand: Vaqora Chemicals
SKU: VQ-039297

About 4-Hydroxy-5-methoxy-2-nitrobenzaldehyde

4-Hydroxy-5-methoxy-2-nitrobenzaldehyde (CAS 2454-72-0) is a metabolite or degradation product of Entacapone offered by Vaqora Chemicals. Formula C8H7NO5, molecular weight 197.14 g/mol. Alternative names: benzaldehyde, 4-hydroxy-5-methoxy-2-nitro- and 6-nitrovanillin.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Entacapone, as well as in QC testing and ANDA/DMF documentation. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 4-Hydroxy-5-methoxy-2-nitrobenzaldehyde in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling
Fine chemical synthesis

Industries

Related to Entacapone

View every impurity, metabolite and intermediate we list for Entacapone.

Entacapone impurities

Specifications & identifiers

Chemical identifiers
Product name	4-Hydroxy-5-methoxy-2-nitrobenzaldehyde
Catalogue No.	VQ-039297
CAS Number	2454-72-0
IUPAC name	4-hydroxy-5-methoxy-2-nitrobenzaldehyde
Molecular formula	C₈H₇NO₅
Molecular weight	197.14 g/mol
Exact mass	197.0324
Grade	Reference Standard
HSN code	38229090
InChIKey	INFACQKUQJGVFF-UHFFFAOYSA-N
SMILES	COC1=C(C=C(C(=C1)C=O)[N+](=O)[O-])O
PubChem CID	220398

Physical properties
Physical form	Solid
LogP (XLogP3)	0.8
H-bond donors / acceptors	1 / 5
TPSA	92.4 Å²
Synonyms	benzaldehyde, 4-hydroxy-5-methoxy-2-nitro-, 6-nitrovanillin, nitro-vanillin, Benzaldehyde,4-hydroxy-5-methoxy-2-nitro-, 2,2':6',2''-Terpyridine,4,4',6''-trimethyl-

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-Hydroxy-5-methoxy-2-nitrobenzaldehyde?

The CAS Registry Number of 4-Hydroxy-5-methoxy-2-nitrobenzaldehyde is 2454-72-0. It is also known as benzaldehyde, 4-hydroxy-5-methoxy-2-nitro-, 6-nitrovanillin, nitro-vanillin.

What is the molecular formula and molecular weight of 4-Hydroxy-5-methoxy-2-nitrobenzaldehyde?

4-Hydroxy-5-methoxy-2-nitrobenzaldehyde has the molecular formula C8H7NO5 and a molecular weight of 197.14 g/mol. Its IUPAC name is 4-hydroxy-5-methoxy-2-nitrobenzaldehyde.

What is 4-Hydroxy-5-methoxy-2-nitrobenzaldehyde used for?

4-Hydroxy-5-methoxy-2-nitrobenzaldehyde is supplied as a characterised reference material related to Entacapone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-Hydroxy-5-methoxy-2-nitrobenzaldehyde can I order?

We supply 4-Hydroxy-5-methoxy-2-nitrobenzaldehyde in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-Hydroxy-5-methoxy-2-nitrobenzaldehyde?

Yes. Every lot of 4-Hydroxy-5-methoxy-2-nitrobenzaldehyde is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-Hydroxy-5-methoxy-2-nitrobenzaldehyde be shipped internationally?

Yes. 4-Hydroxy-5-methoxy-2-nitrobenzaldehyde is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.