Naphthyl Glycidyl Ether

About Naphthyl Glycidyl Ether

Naphthyl Glycidyl Ether is a process intermediate or related compound of Propranolol carrying the CAS registry number 2461-42-9. Its molecular formula is C13H12O2 and its molecular weight is 200.23 g/mol. Its systematic (IUPAC) name is 2-(naphthalen-1-yloxymethyl)oxirane. Alternative names: 2-((Naphthalen-1-yloxy)methyl)oxirane and α-Naphthyl Glycidyl Ether.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

It is a process intermediate or related compound in the synthesis of Propranolol, useful for route development, impurity fate-and-purge studies and analytical method development. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Naphthyl Glycidyl Ether is dispatched with a Certificate of Analysis (COA) to destinations worldwide. Stock is available for quick dispatch.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Propranolol

View every impurity, metabolite and intermediate we list for Propranolol.

Propranolol impurities

Specifications & identifiers

Chemical identifiers
Product name	Naphthyl Glycidyl Ether
Catalogue No.	VQ-013655
CAS Number	2461-42-9
IUPAC name	2-(naphthalen-1-yloxymethyl)oxirane
Molecular formula	C₁₃H₁₂O₂
Molecular weight	200.23 g/mol
Exact mass	200.0837
Grade	Reference Standard
InChIKey	QYYCPWLLBSSFBW-UHFFFAOYSA-N
SMILES	C1C(O1)COC2=CC=CC3=CC=CC=C32
PubChem CID	91521

Physical properties
Physical form	Solid
LogP (XLogP3)	3.3
H-bond donors / acceptors	0 / 2
TPSA	21.8 Å²
Synonyms	2-((Naphthalen-1-yloxy)methyl)oxirane, α-Naphthyl Glycidyl Ether, 2-[[(Naphthalen-1-yl)oxy]methyl]oxirane, 2-[(1-Naphthalenyloxy)methyl]oxirane, 1-(1-Naphthyloxy)-2,3-epoxypropane, 1-(2,3-Epoxypropoxy)naphthalene, 1-(Glycidyloxy)naphthalene, (1-Naphthyloxymethyl)oxirane, (±)-1-(1-Naphthyloxy)-2,3-epoxypropane, 2,3-Epoxypropyl 1-naphthyl ether, 3-(1-Naphthyloxy)-1,2-epoxypropane, 3-(1-Naphthyloxy)propylene oxide

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H335May cause respiratory irritation
H341Suspected of causing genetic defects
H351Suspected of causing cancer

Precautionary statements: P203, P261, P264, P264 + P265, P270, P271, P272, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P318, P319, P321, P330, P332 + P317, P333 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Naphthyl Glycidyl Ether?

The CAS Registry Number of Naphthyl Glycidyl Ether is 2461-42-9. It is also known as 2-((Naphthalen-1-yloxy)methyl)oxirane, α-Naphthyl Glycidyl Ether, 2-[[(Naphthalen-1-yl)oxy]methyl]oxirane.

What is the molecular formula and molecular weight of Naphthyl Glycidyl Ether?

Naphthyl Glycidyl Ether has the molecular formula C13H12O2 and a molecular weight of 200.23 g/mol. Its IUPAC name is 2-(naphthalen-1-yloxymethyl)oxirane.

What is Naphthyl Glycidyl Ether used for?

Naphthyl Glycidyl Ether is supplied as a characterised reference material related to Propranolol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Naphthyl Glycidyl Ether can I order?

We supply Naphthyl Glycidyl Ether in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Naphthyl Glycidyl Ether?

Yes. Every lot of Naphthyl Glycidyl Ether is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Naphthyl Glycidyl Ether be shipped internationally?

Yes. Naphthyl Glycidyl Ether is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.