cis-4-[[(2-Amino-3,5-dibromophenyl)methylene]… 2499966-00-4

About cis-4-[[(2-Amino-3,5-dibromophenyl)methylene]amino]cyclohexanol

cis-4-[[(2-Amino-3,5-dibromophenyl)methylene]amino]cyclohexanol is an impurity of Ambroxol carrying the CAS registry number 2499966-00-4. Formula C13H16Br2N2O, molecular weight 376.09 g/mol. Its systematic (IUPAC) name is 4-[(2-amino-3,5-dibromophenyl)methylideneamino]cyclohexan-1-ol.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Ambroxol to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer cis-4-[[(2-Amino-3,5-dibromophenyl)methylene]amino]cyclohexanol in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Ambroxol

View every impurity, metabolite and intermediate we list for Ambroxol.

Ambroxol impurities

Specifications & identifiers

Chemical identifiers
Product name	cis-4-[[(2-Amino-3,5-dibromophenyl)methylene]amino]cyclohexanol
Catalogue No.	VQ-029094
CAS Number	2499966-00-4
IUPAC name	4-[(2-amino-3,5-dibromophenyl)methylideneamino]cyclohexan-1-ol
Molecular formula	C₁₃H₁₆Br₂N₂O
Molecular weight	376.09 g/mol
Exact mass	375.9609
Grade	Reference Standard
HSN code	38229090
InChIKey	PACIGGABLPTEDO-UHFFFAOYSA-N
SMILES	C1CC(CCC1N=CC2=C(C(=CC(=C2)Br)Br)N)O
PubChem CID	70487064

Physical properties
Physical form	Solid
LogP (XLogP3)	2.8
H-bond donors / acceptors	2 / 3
TPSA	58.6 Å²
Synonyms	trans-4-((2-Amino-3,5-dibromobenzylidene)amino)cyclohexanol, trans-4-[[(E)-2-Amino-3,5-dibromobenzyliden]amino]cyclohexanol, (1R,4R)-4-((E)-2-Amino-3,5-dibromobenzylideneamino)-cyclohexanol, cis-4-(-(2-Amino-3,5-dibromobenzylidene)amino)cyclohexanol, 4-(((2-Amino-3,5-dibromophenyl)methylene)amino)cyclohexanol, trans-, 4-(((E)-2-Amino-3,5-dibromobenzyliden)amino)cyclohexanol, trans-, trans-4-(((2-Amino-3,5-dibromophenyl)methylene)amino)cyclohexanol, Cyclohexanol, 4-(((2-amino-3,5-dibromophenyl)methylene)amino)-, trans-, trans-4-[[(2-Amino-3,5-dibromophenyl)methylene]amino]cyclohexanol, (1r,4r)-4-((E)-(2-Amino-3,5-dibromobenzylidene)amino)cyclohexanol, (1R,4R)-4-((E)-2-amino-3,5-dibromobenzylideneamino)cyclohexanol, (1s,4s)-4-((E)-(2-amino-3,5-dibromobenzylidene)amino)cyclohexanol

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of cis-4-[[(2-Amino-3,5-dibromophenyl)methylene]amino]cyclohexanol?

The CAS Registry Number of cis-4-[[(2-Amino-3,5-dibromophenyl)methylene]amino]cyclohexanol is 2499966-00-4. It is also known as trans-4-((2-Amino-3,5-dibromobenzylidene)amino)cyclohexanol, trans-4-[[(E)-2-Amino-3,5-dibromobenzyliden]amino]cyclohexanol, (1R,4R)-4-((E)-2-Amino-3,5-dibromobenzylideneamino)-cyclohexanol.

What is the molecular formula and molecular weight of cis-4-[[(2-Amino-3,5-dibromophenyl)methylene]amino]cyclohexanol?

cis-4-[[(2-Amino-3,5-dibromophenyl)methylene]amino]cyclohexanol has the molecular formula C13H16Br2N2O and a molecular weight of 376.09 g/mol. Its IUPAC name is 4-[(2-amino-3,5-dibromophenyl)methylideneamino]cyclohexan-1-ol.

What is cis-4-[[(2-Amino-3,5-dibromophenyl)methylene]amino]cyclohexanol used for?

cis-4-[[(2-Amino-3,5-dibromophenyl)methylene]amino]cyclohexanol is supplied as a characterised reference material related to Ambroxol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of cis-4-[[(2-Amino-3,5-dibromophenyl)methylene]amino]cyclohexanol can I order?

We supply cis-4-[[(2-Amino-3,5-dibromophenyl)methylene]amino]cyclohexanol in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with cis-4-[[(2-Amino-3,5-dibromophenyl)methylene]amino]cyclohexanol?

Yes. Every lot of cis-4-[[(2-Amino-3,5-dibromophenyl)methylene]amino]cyclohexanol is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can cis-4-[[(2-Amino-3,5-dibromophenyl)methylene]amino]cyclohexanol be shipped internationally?

Yes. cis-4-[[(2-Amino-3,5-dibromophenyl)methylene]amino]cyclohexanol is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.