Azacitidine impurity N

About Azacitidine impurity N

Azacitidine impurity N is a metabolite or degradation product of Azacitidine carrying the CAS registry number 2508-81-8. The compound has the formula C6H9NO5, corresponding to a molecular weight of 175.14 g/mol. Systematically, it is named (3aS,5R,6R,6aR)-6-hydroxy-5-(hydroxymethyl)-3a,5,6,6a-tetrahydro-3H-furo[2,3-d][1,3]oxazol-2-one. Alternative names: Azacitidine Impurity and D-ribofuranosyl-oxazolidinone.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Analytical teams use this compound to identify metabolites and degradants of Azacitidine, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer Azacitidine impurity N in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Azacitidine

View every impurity, metabolite and intermediate we list for Azacitidine.

Azacitidine impurities

Specifications & identifiers

Chemical identifiers
Product name	Azacitidine impurity N
Catalogue No.	VQ-024462
CAS Number	2508-81-8
IUPAC name	(3aS,5R,6R,6aR)-6-hydroxy-5-(hydroxymethyl)-3a,5,6,6a-tetrahydro-3H-furo[2,3-d][1,3]oxazol-2-one
Molecular formula	C₆H₉NO₅
Molecular weight	175.14 g/mol
Exact mass	175.0481
Grade	Reference Standard
HSN code	38229090
InChIKey	JHLJBMKXTOOGCW-AIHAYLRMSA-N
SMILES	C([C@@H]1[C@H]([C@@H]2[C@H](O1)NC(=O)O2)O)O
PubChem CID	14888193

Physical properties
Physical form	Solid
LogP (XLogP3)	-1.1
H-bond donors / acceptors	3 / 5
TPSA	88 Å²
Synonyms	Azacitidine Impurity, (3as,5r,6r,6ar)-6-hydroxy-5-(hydroxymethyl)-hexahydrofuro[2,3-d][1,3]oxazol-2-one, (3aS,5R,6R,6aR)-6-hydroxy-5-(hydroxymethyl)-hexahydrofuro(2,3-d)(1,3)oxazol-2-one, (3aS,5R,6R,6aR)-6-Hydroxy-5-(hydroxymethyl)tetrahydrofuro[2,3-d]oxazol-2(5H)-one, D-ribofuranosyl-oxazolidinone, (3aS,5R,6R,6aR)-Tetrahydro-6-hydroxy-5-(hydroxymethyl)furo[2,3-d]oxazol-2(3H)-one, Azacitidine Impurity 77

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Azacitidine impurity N?

The CAS Registry Number of Azacitidine impurity N is 2508-81-8. It is also known as Azacitidine Impurity, (3as,5r,6r,6ar)-6-hydroxy-5-(hydroxymethyl)-hexahydrofuro[2,3-d][1,3]oxazol-2-one, (3aS,5R,6R,6aR)-6-hydroxy-5-(hydroxymethyl)-hexahydrofuro(2,3-d)(1,3)oxazol-2-one.

What is the molecular formula and molecular weight of Azacitidine impurity N?

Azacitidine impurity N has the molecular formula C6H9NO5 and a molecular weight of 175.14 g/mol. Its IUPAC name is (3aS,5R,6R,6aR)-6-hydroxy-5-(hydroxymethyl)-3a,5,6,6a-tetrahydro-3H-furo[2,3-d][1,3]oxazol-2-one.

What is Azacitidine impurity N used for?

Azacitidine impurity N is supplied as a characterised reference material related to Azacitidine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Azacitidine impurity N can I order?

We supply Azacitidine impurity N in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Azacitidine impurity N?

Yes. Every lot of Azacitidine impurity N is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Azacitidine impurity N be shipped internationally?

Yes. Azacitidine impurity N is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.