4-Hydroxy Benzothioamide

Name: 4-Hydroxy Benzothioamide
Brand: Vaqora Chemicals
SKU: VQ-032387

About 4-Hydroxy Benzothioamide

4-Hydroxy Benzothioamide (CAS 25984-63-8) is a metabolite or degradation product of Febuxostat offered by Vaqora Chemicals. The compound has the formula C7H7NOS, corresponding to a molecular weight of 153.2 g/mol. Its systematic (IUPAC) name is 4-hydroxybenzenecarbothioamide. Common synonyms include 4-Hydroxythiobenzamide and 4-hydroxy thiobenzamide.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Warning” with 5 hazard statements. Review the Safety Data Sheet before use.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Febuxostat, as well as in QC testing and ANDA/DMF documentation. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 4-Hydroxy Benzothioamide in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling
Fine chemical synthesis

Industries

Related to Febuxostat

View every impurity, metabolite and intermediate we list for Febuxostat.

Febuxostat impurities

Specifications & identifiers

Chemical identifiers
Product name	4-Hydroxy Benzothioamide
Catalogue No.	VQ-032387
CAS Number	25984-63-8
IUPAC name	4-hydroxybenzenecarbothioamide
Molecular formula	C₇H₇NOS
Molecular weight	153.2 g/mol
Exact mass	153.0248
Grade	Reference Standard
HSN code	38229090
InChIKey	VDTNKXSVUGXUOJ-UHFFFAOYSA-N
SMILES	C1=CC(=CC=C1C(=S)N)O
PubChem CID	2759344

Physical properties
Physical form	Solid
LogP (XLogP3)	1.4
H-bond donors / acceptors	2 / 2
TPSA	78.3 Å²
Synonyms	4-Hydroxythiobenzamide, 4-hydroxy thiobenzamide, 4-Hydroxybenzene-1-carbothioamide, p-hydroxythiobenzamide, 4-hydroxythiobenzamide, AldrichCPR, 4-[amino(sulfanyl)methylidene]cyclohexa-2,5-dien-1-one, 4-(aminothioxomethyl)phenol, 4-hydroxybenzene, 4-hydroxy-thiobenzamide, 4-hydroxythio-benzamide

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P272, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P333 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-Hydroxy Benzothioamide?

The CAS Registry Number of 4-Hydroxy Benzothioamide is 25984-63-8. It is also known as 4-Hydroxythiobenzamide, 4-hydroxy thiobenzamide, 4-Hydroxybenzene-1-carbothioamide.

What is the molecular formula and molecular weight of 4-Hydroxy Benzothioamide?

4-Hydroxy Benzothioamide has the molecular formula C7H7NOS and a molecular weight of 153.2 g/mol. Its IUPAC name is 4-hydroxybenzenecarbothioamide.

What is 4-Hydroxy Benzothioamide used for?

4-Hydroxy Benzothioamide is supplied as a characterised reference material related to Febuxostat. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-Hydroxy Benzothioamide can I order?

We supply 4-Hydroxy Benzothioamide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-Hydroxy Benzothioamide?

Yes. Every lot of 4-Hydroxy Benzothioamide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-Hydroxy Benzothioamide be shipped internationally?

Yes. 4-Hydroxy Benzothioamide is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.