5-Methoxysalicylic acid

Name: 5-Methoxysalicylic acid
Brand: Vaqora Chemicals
SKU: VQ-051930

About 5-Methoxysalicylic acid

Listed under CAS 2612-02-4, 5-Methoxysalicylic acid is a process intermediate or related compound of Ascorbic acid available from Vaqora Chemicals. Its molecular formula is C8H8O4 and its molecular weight is 168.15 g/mol. Systematically, it is named 2-hydroxy-5-methoxybenzoic acid. Alternative names: Benzoic acid, 2-hydroxy-5-methoxy- and 5-Methoxy-2-hydroxybenzoic acid.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

It is a process intermediate or related compound in the synthesis of Ascorbic acid, useful for route development, impurity fate-and-purge studies and analytical method development. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 5-Methoxysalicylic acid is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Ascorbic acid

View every impurity, metabolite and intermediate we list for Ascorbic acid.

Ascorbic acid impurities

Specifications & identifiers

Chemical identifiers
Product name	5-Methoxysalicylic acid
Catalogue No.	VQ-051930
CAS Number	2612-02-4
IUPAC name	2-hydroxy-5-methoxybenzoic acid
Molecular formula	C₈H₈O₄
Molecular weight	168.15 g/mol
Exact mass	168.0423
InChIKey	IZZIWIAOVZOBLF-UHFFFAOYSA-N
SMILES	COC1=CC(=C(C=C1)O)C(=O)O
PubChem CID	75787

Physical properties
Physical form	Solid
LogP (XLogP3)	2.5
H-bond donors / acceptors	2 / 4
TPSA	66.8 Å²
Synonyms	Benzoic acid, 2-hydroxy-5-methoxy-, 5-Methoxy-2-hydroxybenzoic acid, Bee Venom Wart Remover Cream, 6-hydroxy-m-anisic acid, Acid5-methoxysalicylic, 5-MeOSA, 5-o-METHYL GENTISIC ACID, m-Anisic acid, 6-hydroxy-, 2-hydroxy-5-methoxy-benzoic acid, 6-hydroxy-3-anisic acid, 2-Hydroxy-5-methoxybenzoicAcid, 5-Methoxysalicylate

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 5-Methoxysalicylic acid?

The CAS Registry Number of 5-Methoxysalicylic acid is 2612-02-4. It is also known as Benzoic acid, 2-hydroxy-5-methoxy-, 5-Methoxy-2-hydroxybenzoic acid, Bee Venom Wart Remover Cream.

What is the molecular formula and molecular weight of 5-Methoxysalicylic acid?

5-Methoxysalicylic acid has the molecular formula C8H8O4 and a molecular weight of 168.15 g/mol. Its IUPAC name is 2-hydroxy-5-methoxybenzoic acid.

What is 5-Methoxysalicylic acid used for?

5-Methoxysalicylic acid is supplied as a characterised reference material related to Ascorbic acid. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 5-Methoxysalicylic acid can I order?

We supply 5-Methoxysalicylic acid, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 5-Methoxysalicylic acid?

Yes. Every lot of 5-Methoxysalicylic acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 5-Methoxysalicylic acid be shipped internationally?

Yes. 5-Methoxysalicylic acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.