4-Methoxyestradiol

Name: 4-Methoxyestradiol
Brand: Vaqora Chemicals
SKU: VQ-048296

About 4-Methoxyestradiol

Vaqora Chemicals supplies 4-Methoxyestradiol, a process intermediate or related compound of Ethinylestradiol registered under CAS number 26788-23-8. Formula C19H26O3, molecular weight 302.4 g/mol. The IUPAC name is (8R,9S,13S,14S,17S)-4-methoxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol. Alternative names: 4-Methoxyestradiol-17beta and 4-MeOE2.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

It is a process intermediate or related compound in the synthesis of Ethinylestradiol, useful for route development, impurity fate-and-purge studies and analytical method development. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Ethinylestradiol

View every impurity, metabolite and intermediate we list for Ethinylestradiol.

Ethinylestradiol impurities

Specifications & identifiers

Chemical identifiers
Product name	4-Methoxyestradiol
Catalogue No.	VQ-048296
CAS Number	26788-23-8
IUPAC name	(8R,9S,13S,14S,17S)-4-methoxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol
Molecular formula	C₁₉H₂₆O₃
Molecular weight	302.4 g/mol
Exact mass	302.1882
InChIKey	BCWZIZLVBYHFES-PYEWSWHRSA-N
SMILES	C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)CCC4=C3C=CC(=C4OC)O
PubChem CID	68578

Physical properties
Physical form	Solid
LogP (XLogP3)	4
H-bond donors / acceptors	2 / 3
TPSA	49.7 Å²
Synonyms	4-Methoxyestradiol-17beta, 4-MeOE2, Estra-1,3,5(10)-triene-3,17-diol, 4-methoxy-, (17beta)-, 4-methoxyestradiol-17 beta, 4-MeE2, 4-methoxy-17beta-estradiol, 4-Methoxy 17beta-estradiol, 4-Methoxy 17b-Estradiol, 4-methoxyestra-1,3,5(10)-triene-3,17beta-diol, 4-Methoxy-3,17beta-dihydroxy-1,3,5[10]-estratriene, (17beta)-4-methoxyestra-1,3,5(10)-triene-3,17-diol

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-Methoxyestradiol?

The CAS Registry Number of 4-Methoxyestradiol is 26788-23-8. It is also known as 4-Methoxyestradiol-17beta, 4-MeOE2, Estra-1,3,5(10)-triene-3,17-diol, 4-methoxy-, (17beta)-.

What is the molecular formula and molecular weight of 4-Methoxyestradiol?

4-Methoxyestradiol has the molecular formula C19H26O3 and a molecular weight of 302.4 g/mol. Its IUPAC name is (8R,9S,13S,14S,17S)-4-methoxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol.

What is 4-Methoxyestradiol used for?

4-Methoxyestradiol is supplied as a characterised reference material related to Ethinylestradiol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-Methoxyestradiol can I order?

We supply 4-Methoxyestradiol, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-Methoxyestradiol?

Yes. Every lot of 4-Methoxyestradiol is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-Methoxyestradiol be shipped internationally?

Yes. We export 4-Methoxyestradiol worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.