1,4-Anhydro-D-sorbitol

Name: 1,4-Anhydro-D-sorbitol
Brand: Vaqora Chemicals
SKU: VQ-038958

About 1,4-Anhydro-D-sorbitol

1,4-Anhydro-D-sorbitol is a process intermediate or related compound of Sorbitol carrying the CAS registry number 27299-12-3. With the molecular formula C6H12O5, it has a molar mass of 164.16 g/mol. Its systematic (IUPAC) name is (2R,3R,4S)-2-[(1R)-1,2-dihydroxyethyl]oxolane-3,4-diol. Common synonyms include 1,4-Sorbitan and 1,4-Anhydro-D-glucitol.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

It is a process intermediate or related compound in the synthesis of Sorbitol, useful for route development, impurity fate-and-purge studies and analytical method development. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 1,4-Anhydro-D-sorbitol in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development
Fine chemical synthesis

Industries

Related to Sorbitol

View every impurity, metabolite and intermediate we list for Sorbitol.

Sorbitol impurities

Specifications & identifiers

Chemical identifiers
Product name	1,4-Anhydro-D-sorbitol
Catalogue No.	VQ-038958
CAS Number	27299-12-3
IUPAC name	(2R,3R,4S)-2-[(1R)-1,2-dihydroxyethyl]oxolane-3,4-diol
Molecular formula	C₆H₁₂O₅
Molecular weight	164.16 g/mol
Exact mass	164.0685
InChIKey	JNYAEWCLZODPBN-JGWLITMVSA-N
SMILES	C1[C@@H]([C@H]([C@H](O1)[C@@H](CO)O)O)O
PubChem CID	10953859

Physical properties
Physical form	Solid
LogP (XLogP3)	-2.1
H-bond donors / acceptors	4 / 5
TPSA	90.2 Å²
Synonyms	1,4-Sorbitan, 1,4-Anhydro-D-glucitol, 1,4-anhydrosorbitol, 1,4-Anhydroglucitol, D-Glucitol, 1,4-anhydro-, (2R,3R,4S)-2-((R)-1,2-Dihydroxyethyl)tetrahydrofuran-3,4-diol, Glucitol, 1,4-anhydro-, (2R,3R,4S)-2-[(1R)-1,2-dihydroxyethyl]tetrahydrofuran-3,4-diol

Safety & hazard information (GHS)

Toxic

Harmful / irritant

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H319Causes serious eye irritation

Precautionary statements: P264, P264 + P265, P270, P280, P301 + P316, P305 + P351 + P338, P321, P330, P337 + P317, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 1,4-Anhydro-D-sorbitol?

The CAS Registry Number of 1,4-Anhydro-D-sorbitol is 27299-12-3. It is also known as 1,4-Sorbitan, 1,4-Anhydro-D-glucitol, 1,4-anhydrosorbitol.

What is the molecular formula and molecular weight of 1,4-Anhydro-D-sorbitol?

1,4-Anhydro-D-sorbitol has the molecular formula C6H12O5 and a molecular weight of 164.16 g/mol. Its IUPAC name is (2R,3R,4S)-2-[(1R)-1,2-dihydroxyethyl]oxolane-3,4-diol.

What is 1,4-Anhydro-D-sorbitol used for?

1,4-Anhydro-D-sorbitol is supplied as a characterised reference material related to Sorbitol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 1,4-Anhydro-D-sorbitol can I order?

We supply 1,4-Anhydro-D-sorbitol, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 1,4-Anhydro-D-sorbitol?

Yes. Every lot of 1,4-Anhydro-D-sorbitol is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 1,4-Anhydro-D-sorbitol be shipped internationally?

Yes. 1,4-Anhydro-D-sorbitol is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.