4,4'-(2,5-Dioxopiperazine-1,4-diyl)dibenzonit… 2733025-09-5

About 4,4'-(2,5-Dioxopiperazine-1,4-diyl)dibenzonitrile

4,4'-(2,5-Dioxopiperazine-1,4-diyl)dibenzonitrile is an impurity of Dabigatran carrying the CAS registry number 2733025-09-5. Its molecular formula is C18H12N4O2 and its molecular weight is 316.3 g/mol. The IUPAC name is 4-[4-(4-cyanophenyl)-2,5-dioxopiperazin-1-yl]benzonitrile.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

This Dabigatran impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 4,4'-(2,5-Dioxopiperazine-1,4-diyl)dibenzonitrile is dispatched with a Certificate of Analysis (COA) to destinations worldwide. A Safety Data Sheet (SDS) and technical specifications are available on request.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Dabigatran

View every impurity, metabolite and intermediate we list for Dabigatran.

Dabigatran impurities

Specifications & identifiers

Chemical identifiers
Product name	4,4'-(2,5-Dioxopiperazine-1,4-diyl)dibenzonitrile
Catalogue No.	VQ-045077
CAS Number	2733025-09-5
IUPAC name	4-[4-(4-cyanophenyl)-2,5-dioxopiperazin-1-yl]benzonitrile
Molecular formula	C₁₈H₁₂N₄O₂
Molecular weight	316.3 g/mol
Exact mass	316.096
Grade	Reference Standard
HSN code	38229090
InChIKey	SRMGTRQYZAYILR-UHFFFAOYSA-N
SMILES	C1C(=O)N(CC(=O)N1C2=CC=C(C=C2)C#N)C3=CC=C(C=C3)C#N
PubChem CID	124222861

Physical properties
Physical form	Solid
LogP (XLogP3)	1.6
H-bond donors / acceptors	0 / 4
TPSA	88.2 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4,4'-(2,5-Dioxopiperazine-1,4-diyl)dibenzonitrile?

The CAS Registry Number of 4,4'-(2,5-Dioxopiperazine-1,4-diyl)dibenzonitrile is 2733025-09-5. It is also known as 4-(4-(4-Isocyanophenyl)-2,5-dioxopiperazin-1-yl)benzonitrile.

What is the molecular formula and molecular weight of 4,4'-(2,5-Dioxopiperazine-1,4-diyl)dibenzonitrile?

4,4'-(2,5-Dioxopiperazine-1,4-diyl)dibenzonitrile has the molecular formula C18H12N4O2 and a molecular weight of 316.3 g/mol. Its IUPAC name is 4-[4-(4-cyanophenyl)-2,5-dioxopiperazin-1-yl]benzonitrile.

What is 4,4'-(2,5-Dioxopiperazine-1,4-diyl)dibenzonitrile used for?

4,4'-(2,5-Dioxopiperazine-1,4-diyl)dibenzonitrile is supplied as a characterised reference material related to Dabigatran. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4,4'-(2,5-Dioxopiperazine-1,4-diyl)dibenzonitrile can I order?

We supply 4,4'-(2,5-Dioxopiperazine-1,4-diyl)dibenzonitrile in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4,4'-(2,5-Dioxopiperazine-1,4-diyl)dibenzonitrile?

Yes. Every lot of 4,4'-(2,5-Dioxopiperazine-1,4-diyl)dibenzonitrile is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4,4'-(2,5-Dioxopiperazine-1,4-diyl)dibenzonitrile be shipped internationally?

Yes. We export 4,4'-(2,5-Dioxopiperazine-1,4-diyl)dibenzonitrile worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.