1-(4,4'-Dichlorobenzhydryl)piperazine

Name: 1-(4,4'-Dichlorobenzhydryl)piperazine
Brand: Vaqora Chemicals
SKU: VQ-032431

About 1-(4,4'-Dichlorobenzhydryl)piperazine

1-(4,4'-Dichlorobenzhydryl)piperazine (CAS 27469-61-0) is a process intermediate or related compound of Cetirizine offered by Vaqora Chemicals. Formula C17H18Cl2N2, molecular weight 321.2 g/mol. Its systematic (IUPAC) name is 1-[bis(4-chlorophenyl)methyl]piperazine. Common synonyms include 1-(Bis(4-chlorophenyl)methyl)piperazine and Piperazine, 1-[bis(4-chlorophenyl)methyl]-.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

It is a process intermediate or related compound in the synthesis of Cetirizine, useful for route development, impurity fate-and-purge studies and analytical method development. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 1-(4,4'-Dichlorobenzhydryl)piperazine in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development
Fine chemical synthesis

Industries

Related to Cetirizine

View every impurity, metabolite and intermediate we list for Cetirizine.

Cetirizine impurities

Specifications & identifiers

Chemical identifiers
Product name	1-(4,4'-Dichlorobenzhydryl)piperazine
Catalogue No.	VQ-032431
CAS Number	27469-61-0
IUPAC name	1-[bis(4-chlorophenyl)methyl]piperazine
Molecular formula	C₁₇H₁₈Cl₂N₂
Molecular weight	321.2 g/mol
Exact mass	320.0847
HSN code	2933
InChIKey	PTLFMGDNZYQISN-UHFFFAOYSA-N
SMILES	C1CN(CCN1)C(C2=CC=C(C=C2)Cl)C3=CC=C(C=C3)Cl
PubChem CID	285510

Physical properties
Physical form	Solid
LogP (XLogP3)	4.1
H-bond donors / acceptors	1 / 2
TPSA	15.3 Å²
Synonyms	1-(Bis(4-chlorophenyl)methyl)piperazine, Piperazine, 1-[bis(4-chlorophenyl)methyl]-, 4,4'-Dichlorobenzhydrylpiperazine, 1-[Bis-(4-chloro-phenyl)-methyl]-piperazine, 4-(bis(4-chlorophenyl)methyl)piperazine, 4-[Bis(4-chlorophenyl)methyl]piperazine, bis(4-chlorophenyl)methylpiperazine, 1-(4,4 inverted exclamation mark -Dichlorobenzhydryl)piperazine

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Health hazard

Environmental hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H317May cause an allergic skin reaction
H318Causes serious eye damage
H319Causes serious eye irritation
H335May cause respiratory irritation
H361Suspected of damaging fertility or the unborn child
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects
H411Toxic to aquatic life with long lasting effects

Precautionary statements: P203, P261, P264, P264 + P265, P270, P271, P272, P273, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P305 + P354 + P338, P317, P318, P319, P321, P330, P332 + P317, P333 + P317, P337 + P317, P362 + P364, P391

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 1-(4,4'-Dichlorobenzhydryl)piperazine?

The CAS Registry Number of 1-(4,4'-Dichlorobenzhydryl)piperazine is 27469-61-0. It is also known as 1-(Bis(4-chlorophenyl)methyl)piperazine, Piperazine, 1-[bis(4-chlorophenyl)methyl]-, 4,4'-Dichlorobenzhydrylpiperazine.

What is the molecular formula and molecular weight of 1-(4,4'-Dichlorobenzhydryl)piperazine?

1-(4,4'-Dichlorobenzhydryl)piperazine has the molecular formula C17H18Cl2N2 and a molecular weight of 321.2 g/mol. Its IUPAC name is 1-[bis(4-chlorophenyl)methyl]piperazine.

What is 1-(4,4'-Dichlorobenzhydryl)piperazine used for?

1-(4,4'-Dichlorobenzhydryl)piperazine is supplied as a characterised reference material related to Cetirizine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 1-(4,4'-Dichlorobenzhydryl)piperazine can I order?

We supply 1-(4,4'-Dichlorobenzhydryl)piperazine, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 1-(4,4'-Dichlorobenzhydryl)piperazine?

Yes. Every lot of 1-(4,4'-Dichlorobenzhydryl)piperazine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 1-(4,4'-Dichlorobenzhydryl)piperazine be shipped internationally?

Yes. 1-(4,4'-Dichlorobenzhydryl)piperazine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.