2-(3,4-Dimethylphenyl)-5-methyl-1H-pyrazol-3(… 277299-70-4

Name: 2-(3,4-Dimethylphenyl)-5-methyl-1H-pyrazol-3(2H)-one
Brand: Vaqora Chemicals
SKU: VQ-025511

About 2-(3,4-Dimethylphenyl)-5-methyl-1H-pyrazol-3(2H)-one

Vaqora Chemicals supplies 2-(3,4-Dimethylphenyl)-5-methyl-1H-pyrazol-3(2H)-one, an impurity of Eltrombopag registered under CAS number 277299-70-4. With the molecular formula C12H14N2O, it has a molar mass of 202.25 g/mol. The IUPAC name is 2-(3,4-dimethylphenyl)-5-methyl-1H-pyrazol-3-one. It is also known as 1-(3,4-Dimethylphenyl)-3-methyl-5-pyrazolone or 1-(3,4-dimethylphenyl)-3-methylpyrazol-5-ol.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Warning” with 4 hazard statements. Review the Safety Data Sheet before use.

This Eltrombopag impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 2-(3,4-Dimethylphenyl)-5-methyl-1H-pyrazol-3(2H)-one in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Eltrombopag

View every impurity, metabolite and intermediate we list for Eltrombopag.

Eltrombopag impurities

Specifications & identifiers

Chemical identifiers
Product name	2-(3,4-Dimethylphenyl)-5-methyl-1H-pyrazol-3(2H)-one
Catalogue No.	VQ-025511
CAS Number	277299-70-4
IUPAC name	2-(3,4-dimethylphenyl)-5-methyl-1H-pyrazol-3-one
Molecular formula	C₁₂H₁₄N₂O
Molecular weight	202.25 g/mol
Exact mass	202.1106
Grade	Reference Standard
HSN code	38229090
InChIKey	HBWBJCSXUJIDGN-UHFFFAOYSA-N
SMILES	CC1=C(C=C(C=C1)N2C(=O)C=C(N2)C)C
PubChem CID	11735829

Physical properties
Physical form	Solid
LogP (XLogP3)	2.6
H-bond donors / acceptors	1 / 2
TPSA	32.3 Å²
Synonyms	2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one, 3H-Pyrazol-3-one, 2-(3,4-dimethylphenyl)-1,2-dihydro-5-methyl-, 2-(3,4-Dimethyl-phenyl)-5-methyl-1,2-dihydro-pyrazol-3-one, 1-(3,4-Dimethylphenyl)-3-methyl-3-pyrazolin-5-one, 1-(3,4-dimethylphenyl)-3-methyl-1H-pyrazol-5-ol, 2-(3,4-dimethylphenyl)-5-methyl-1,2-dihydro-3H-pyrazol-3-one, 1-(3,4-Dimethylphenyl)-3-methyl-5-pyrazolone, 1-(3,4-dimethylphenyl)-3-methylpyrazol-5-ol, 2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl, 2-(3,4-dimethylphenyl)-5-methyl-2,3-dihydro-1H-pyrazol-3-one

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2-(3,4-Dimethylphenyl)-5-methyl-1H-pyrazol-3(2H)-one?

The CAS Registry Number of 2-(3,4-Dimethylphenyl)-5-methyl-1H-pyrazol-3(2H)-one is 277299-70-4. It is also known as 2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one, 3H-Pyrazol-3-one, 2-(3,4-dimethylphenyl)-1,2-dihydro-5-methyl-, 2-(3,4-Dimethyl-phenyl)-5-methyl-1,2-dihydro-pyrazol-3-one.

What is the molecular formula and molecular weight of 2-(3,4-Dimethylphenyl)-5-methyl-1H-pyrazol-3(2H)-one?

2-(3,4-Dimethylphenyl)-5-methyl-1H-pyrazol-3(2H)-one has the molecular formula C12H14N2O and a molecular weight of 202.25 g/mol. Its IUPAC name is 2-(3,4-dimethylphenyl)-5-methyl-1H-pyrazol-3-one.

What is 2-(3,4-Dimethylphenyl)-5-methyl-1H-pyrazol-3(2H)-one used for?

2-(3,4-Dimethylphenyl)-5-methyl-1H-pyrazol-3(2H)-one is supplied as a characterised reference material related to Eltrombopag. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2-(3,4-Dimethylphenyl)-5-methyl-1H-pyrazol-3(2H)-one can I order?

We supply 2-(3,4-Dimethylphenyl)-5-methyl-1H-pyrazol-3(2H)-one in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2-(3,4-Dimethylphenyl)-5-methyl-1H-pyrazol-3(2H)-one?

Yes. Every lot of 2-(3,4-Dimethylphenyl)-5-methyl-1H-pyrazol-3(2H)-one is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2-(3,4-Dimethylphenyl)-5-methyl-1H-pyrazol-3(2H)-one be shipped internationally?

Yes. 2-(3,4-Dimethylphenyl)-5-methyl-1H-pyrazol-3(2H)-one is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.